Sevelamer Carbonate CAS 845273-93-0 API Factory High Purity
Ubonelelo lwabavelisi ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama leKhemikhali: Sevelamer Carbonate
CAS: 845273-93-0
I-Sevelamer Carbonate yi-amine ye-polymeric ebopha i-phosphate kwaye isetyenziselwa ukunyanga i-hyperphosphatemia kwizigulana ezinesifo sezintso ezingapheliyo.
Umgangatho ophezulu we-API, iMveliso yoRhwebo
Igama leMchiza | Sevelamer carbonate |
Izithethantonye | I-2-Propen-1-Amine Polymer ene (Chloromethyl)Oxirane Carbonate |
Inombolo yeCAS | 845273-93-0 |
Inombolo yeCAT | RF-API28 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | (C3H7N)m.(C3H5ClO)n.(CH2O3)x |
Ubunzima beMolekyuli | 211.64 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe ukuya koMthubi |
Isazisi A | Nge-IR, Ukuhambelana nomgangatho wokusebenza |
Isazisi B | Kufuneka impendulo entle |
I-Chloride | ≤0.10% |
Ilahleko ekomisweni | ≤10.0% |
Intsalela kwi-Ignition | ≤0.20% |
Iintsimbi ezinzima | ≤20ppm |
Uvavanyo lokunyibilika | Kufuneka ihambelane nomgangatho |
Ukubophelela kwePhosphate | 3.0~7.0mmol/g |
I-Oligomer enyibilikayo | ≤0.20% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ingqalelo | Khusela ekukhanyeni kwaye Gcina kwindawo epholileyo eyomileyo (≤5 ℃), Eyona nto isetyenziswayo kwiinyanga ezintandathu |
Ukusetyenziswa | I-Active Pharmaceutical ingredient (API) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
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I-Sevelamer carbonate yi-amine ye-polymeric ebopha i-phosphate kwaye isetyenziselwa ukunyanga i-HYPERPHOSPHATEMIA kwizigulane ezinesifo sezintso.I-Sevelamer carbonate yi-anion exchange resin, kunye nesakhiwo esifanayo se-polymeric njenge-sevelamer hydrochloride, apho i-carbonate ithatha indawo ye-chloride njenge-counterion.Ngelixa i-counterions ihluke kwiityuwa ezimbini, i-polymer ngokwayo, i-moiety esebenzayo ebandakanyekayo kwi-phosphate binding, iyafana.I-Sevelamer carbonate yaziwa ngokwekhemikhali njenge-poly(allylamine-co-N,N'-diallyl-1,3diamino-2-hydroxypropane) ityuwa ye-carbonate.I-Sevelamer carbonate i-hygroscopic, kodwa ayinyibiliki emanzini.ISevelamer Carbonate, ipolymer engafunxwanga sisidibanisi sephosphate yomlomo kubaguli abanengxaki yezintso.Kunikelwa ingxelo yokuba iSevelamer Carbonate ayinakufane ibangele i-hypercalcemia, umlinganiselo ophantsi wePTH, kunye nokwanda kwe-coronary and aortic calcification kubaguli be-hemodialysis kune-calcium-based phosphate binder.
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