I-Sitagliptin CAS 486460-32-6 Ucoceko >99.0% (HPLC) API Factory High Purity
Ubonelelo ngeSitagliptin Phosphate Monohydrate Eziyeleleneyo neziPhakathi:
I-Sitagliptin API CAS 486460-32-6
I-Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6
I-Sitagliptin Phosphate Monohydrate ePhakathi CAS 486460-21-3
Igama leMchiza | I-Sitagliptin |
Izithethantonye | (3R) -3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4- (2,4,5-trifluorophenyl)butan-1-enye |
Inombolo yeCAS | 486460-32-6 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C16H15F6N5O |
Ubunzima beMolekyuli | 407.31 |
Indawo yokunyibilika | 114.0 ~ 115.0℃ |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kuMhlophe oMhlophe wePowder |
Ukuchongwa yi-HPLC | Ixesha lokuGcinwa kweSampuli lihambelana noMgangatho weReferensi |
Ilahleko ekomisweni | <1.0% |
Intsalela kwi-Ignition | <0.20% |
Izinto ezinxulumeneyo | |
Nakuphi na Ukungacoceki Okukodwa | <0.50% |
Ukungcola ngokupheleleyo | <1.0% |
Ubunyulu | >99.0% (HPLC) |
Ucoceko lwe-Enantiomeric | <0.50% |
Iintsimbi ezinzima | <20ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | API;Uhlobo lwe-II yesifo seswekile i-Mellitus |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
I-Sitagliptin (CAS: 486460-32-6), njengohlobo olutsha lwechiza le-antidiabetic, i-Sitagliptin Phosphate ineenzuzo zokuxhomekeka kwe-glucose, i-moderate hypoglycemic effect, i-secretion eyongeziweyo ngaphandle kwe-hypoglycemia, iyancipha ngokufanelekileyo indlala, kwaye ayizange ibe nemiphumo emibi efana nesicaphucaphu, ukuhlanza, i-edema kunye nokwanda kobunzima bomzimba.I-Sitagliptin phosphate njengonyango lwechiza olunye kwizigulana ezinohlobo lwe-II yeswekile inokwehlisa kakhulu inqanaba le-glycosylated hemoglobin (HbA1c).Yi-dipeptidyl peptidase-4 (DPP-4) inhibitor, enokuphucula amandla omzimba womntu ukunciphisa izinga le-glucose ephezulu yegazi.I-Sitagliptin yaphuhliswa yi-Merck & Co. kwaye yamkelwa ukuba isetyenziswe kwezonyango e-United States ngo-2006.