I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Ubunyulu >99.0% (HPLC) Factory High Quality Featured Image

I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Ubunyulu >99.0% (HPLC) Umzi-mveliso oPhezulu oPhezulu

Inkcazelo emfutshane:

Igama: I-Sitagliptin Triazole Hydrochloride

CAS: 762240-92-6

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Mhlophe ukuya kuMhlophe-Mhlophe wePowder

I-Intermediate ye-Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) yonyango lwe-II diabetes mellitus

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo ngeSitagliptin Phosphate Monohydrate Eziyeleleneyo neziPhakathi:
I-Sitagliptin API CAS 486460-32-6
I-Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6
I-Sitagliptin Phosphate Monohydrate ePhakathi CAS 486460-21-3

Iipropati zeMichiza:

Igama leMchiza	3-(Trifluoromethyl) -5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride
Izithethantonye	iSitagliptin Triazole Hydrochloride;ISitagliptin ePhakathi A
Inombolo yeCAS	762240-92-6
Inombolo yeCAT	RF-PI1193
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C6H7F3N4·HCl
Ubunzima beMolekyuli	228.60
Indawo yokunyibilika	236.0 ~ 246.0℃
Ukunyibilika	Inyibilika kwiMethanol
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya kuMhlophe-Mhlophe wePowder
Ukuchongwa yi-HPLC	Ixesha lokugcinwa kwesampulu lihambelana nomgangatho wereferensi
Ukuchongwa nge-IR	Iyahambelana
Ilahleko ekomisweni	<0.50%
Izinto ezinxulumeneyo
Nakuphi na Ukungacoceki Okukodwa	<0.50%
Ukungcola ngokupheleleyo	<1.00%
Iintsimbi ezinzima	<20ppm
Ubunyulu / Indlela yokuHlalutya	>99.0% (HPLC)
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi weSitagliptin Phosphate Monohydrate (CAS: 654671-77-9)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.

Izinto eziluncedo:

FAQ:

Isicelo:

I-3-(Trifluoromethyl) -5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride (CAS: 762240-92-6) iphakathi kweSitagliptin Phosphate Monohydrate ( I-CAS: 654671-77-9), eyi-oral-bioavailable selective DPP4 inhibitor efunyenwe ngokulungiswa kweklasi ye-β-aminoacid-derived DPP4 inhibitors.Yehlisa umsebenzi we-DPP4 ngendlela ezinzileyo elandela ulawulo kube kanye yonke imihla, igcina amanqanaba ajikelezayo e-GIP engaguqukiyo kunye ne-GLP1 emva kokutya kwizifundo ezibukhali nezingapheliyo kwaye yehlisa amanqanaba eglucose yegazi ngaphandle kokunyuka okubonakalayo kwe-hypoglycaemia.I-Sitagliptin Phosphate (STG) isetyenziselwa ukuphatha uhlobo lwe-DM ye-2 kuba iphucula ulawulo lwe-glycemic ngokunyusa amanqanaba e-hormone ye-incretin esebenzayo, i-GLP-1 (peptide-1) kunye ne-GIP (i-glucose-exhomekeke kwi-insulinotropic peptide).I-STG yavunywa yi-FDA kwi-2006.