I-Sodium 4-Aminosalicylate CAS 133-10-8 Ubunyulu > 99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-Sodium 4-Aminosalicylate (i-CAS: 133-10-8) enomgangatho ophezulu.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha lubandakanya inombolo ye-CAS, igama lemveliso, ubuninzi kuthi.Please contact: alvin@ruifuchem.com
Igama leMchiza | I-Sodium 4-Aminosalicylate |
Izithethantonye | I-4-Amino-Salicylic Acid Ityuwa yeSodium;I-4-Amino-2-Hydroxybenzoic Acid yeTyuwa yeSodium;I-4-Aminosalicylic Acid Ityuwa yeSodium;Isodium p-Aminosalicylate;p-Aminosalicylic Acid Sodium iTyuwa |
Inombolo yeCAS | 133-10-8 |
Inombolo yeCAT | RF2771 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C7H6NNaO3 |
Ubunzima beMolekyuli | 175.12 |
Indawo yokunyibilika | 265.0~270.0℃ |
Inovakalelo | Hygroscopic |
Ukunyibilika | Inyibilika ngokulula emanzini, iNyibilika kancinane kwi-Ethanol, ayinyibiliki kwi-acetone |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline oMhlophe okanye oMhlophe |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) |
Amanzi (nguKarl Fischer) | <2.00% |
3-Aminophenol | <0.25% |
Ukungcola ngokupheleleyo | <1.00% |
I-Infrared Spectrum | Iyahambelana neSakhiwo |
Proton NMR Spectrum | Iyahambelana neSakhiwo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | abaPhakathi bamayeza;Iarhente yeAntitubercular |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
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I-sodium 4-Aminosalicylate (i-CAS: 133-10-8) i-soluble ngokulula emanzini, i-soluble kancinane kwi-ethanol, i-insoluble kwi-acetone.Ingasetyenziswa njengamachiza achasene nesifo sephepha, ingakumbi kunyango olubanzi losulelo lwesifo sephepha.Le mveliso ifana ne-4-Aminobenzoic acid (PABA) kwisakhiwo, i-congener ye-PABA.Ithintela ukukhula kunye nokuveliswa kwesifo sephepha seMycobacterium ngokuthintela ukhuphiswano lwe-folate synthesis.Le mveliso isebenza kuphela kwi-mycobacteria, kungekhona i-mycobacteria ye-atypical.Xa isetyenziswa yodwa, inokukhula ngokukhawuleza ukunganyangeki kumachiza.Le mveliso kufuneka idityaniswe namanye amachiza okulwa nesifo sephepha, anjengestreptomycin kunye ne-isoniazid, ezinokulibazisa ukuveliswa kokumelana namachiza kwi-bacilli yesifo sephepha ukuya kwezi zibini zokugqibela.Ngokonyango, isetyenziselwa ikakhulu isifo sephepha semiphunga kunye nesangaphandle kwemiphunga esibangelwa sisifo sephepha iMycobacterium.Ikwasetyenziswa kwi-hyperthyroidism kwaye inefuthe elinamandla ekunciphiseni i-lipids yegazi.Ifakwe kakuhle kwiphecana le-GI.Ifunxwa ngokukhawuleza ngakumbi kunezinye i-salicylic acids.Emva kokufunxwa, isasazwa ngokukhawuleza kulwelo olwahlukeneyo lomzimba kwaye ifikelela kugxininiso oluphezulu kakhulu kulwelo lwe-pleural, kodwa ugxininiso kulwelo lwe-cerebrospinal luphantsi kakhulu.Imveliso isasazeka ngokukhawuleza kwizintso, imiphunga kunye nezicubu zesibindi, ifikelela kwiindawo eziphezulu kwii-caseous tissues.Ifanelekile kwi-pulmonary and extrapulmonary tuberculosis ebangelwa yi-Mycobacterium tuberculosis.I-sodium para-aminosalicylate iyasebenza kuphela ngokuchasene ne-mycobacteria kwaye hayi ngokuchasene ne-mycobacteria engekhoyo.Ukunganyangeki kungakhula ngokukhawuleza xa isetyenziswa yodwa, ngoko ke kufuneka idityaniswe namanye amachiza alwa ne-TB.I-Streptomycin kunye ne-isoniazid, xa zidityanisiwe nazo, zinokulibazisa ukukhula kokunganyangeki ngamachiza kwe-Mycobacterium tuberculosis kula machiza mabini.Isetyenziswa kakhulu njengechiza elichasene nesifo sephepha kumgca wesibini.Ingasetyenziselwa i-hyperthyroidism, kwaye ifanelekile kwizigulana ezine-hyperthyroidism kunye nesifo sephepha.Xa i-agent ye-iodine ingasebenzi kwaye ichaphazela ukusebenza, inokuthatyathwa ixesha elifutshane ukudala iimeko zokusebenza.Ukufakwa kwi-intravenous ngokuqhelekileyo kusetyenziswa kwiimeko ezinzima ezifana ne-tuberculous meningitis.