I-Sodium 4-Aminosalicylate Dihydrate CAS 6018-19-5 Ubunyulu > 99.0% (HPLC) (T)

Inkcazelo emfutshane:

Igama leKhemikhali: I-Sodium 4-Aminosalicylate Dihydrate

CAS: 6018-19-5

Ubunyulu: >99.0% (HPLC) (T)

Umgubo weCrystalline oMhlophe okanye oMhlophe okanye oMhlophe

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Inkcazo:

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Iipropati zeMichiza:

Igama leMchiza I-Sodium 4-Aminosalicylate Dihydrate
Izithethantonye I-4-Amino-2-Hydroxybenzoic Acid Sodium Salt Dihydrate;I-4-Aminosalicylic Acid Sodium Salt Dihydrate;Sodium p-Aminosalicylate Dihydrate;p-Aminosalicylic Acid Sodium yeTyuwa Dihydrate
Inombolo yeCAS 6018-19-5
Inombolo yeCAT RF2770
Ubume beStokhwe KwiSitokhwe, Umthamo weMveliso iiToni ezingama-35 ngenyanga
Ifomula yeemolekyuli C7H6NNaO3·2H2O
Ubunzima beMolekyuli 211.15
Indawo yokunyibilika 250℃
Inovakalelo UkuKhanya okungevayo, ukungeva komoya
Ukunyibilika emanzini Inyibilika ngokulula kuManzi (956g/l), Phantse iNgaphandle
Ukunyibilika Inyibilika kancinane kwi-Ethanol, kwaye ayinyibiliki kwi-Diethyl Ether
Ivumba Ayinavumba, Incasa eSwiti netyiwayo
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Umgubo weCrystalline oMhlophe okanye oMhlophe okanye oMhlophe
Ukuchongwa Iyahlangabezana neeMfuno
Ubunyulu / Indlela yokuHlalutya >99.0% (HPLC)
Ubunyulu / Indlela yokuHlalutya >98.5% (Nonaqueous Titration)
Amanzi (nguKarl Fischer) 16.0 ukuya kwi-18.0%
Nitrogen ngu-ElementalAnalysis 7.3~8.6% (Amanzi)
Ikhabhoni ngohlalutyo lwe-Elemental 46.5 ~ 48.5% (Amanzi)
Iintsimbi ezinzima (njenge Pb) <0.001%
Ikloridi (Cl) <0.005%
Sulfate <0.001%
Intsimbi (Fe) <0.0015%
IArsenic (As) <0.0002%
Izinto eziluhlaza 3-Aminophenol <0.25%
Ukungcola ngokupheleleyo <1.00%
Ixabiso le-pH 6.5~8.5 (20g/l, H2O, 20℃)
I-Infrared Spectrum Iyahambelana neSakhiwo
Ukunyibilika kwisisombululo se-H2O Ipasile ecacileyo
Umgangatho woVavanyo Umgangatho woShishino
Beka ubomi kwishelufa Iminyaka emibini
Ukusetyenziswa Iarhente yeAntitubercular

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Isicelo:

I-sodium 4-Aminosalicylate Dihydrate (i-CAS: 6018-19-5) yi-antibiotic esetyenziselwa ukunyanga isifo sofuba nge-NF-κB inhibition kunye ne-free radical scavenging.I-Antibacterial, i-tuberculostatic.I-sodium 4-Aminosalicylate Dihydrate isetyenziswa ngokuqhelekileyo njengeyeza elichasayo isifo sephepha.Ifanelekile kwi-pulmonary and extrapulmonary tuberculosis ebangelwa yi-Mycobacterium tuberculosis.Ngenxa yokuba intsholongwane yesifo sephepha inokunganyangeki ngokukhawuleza xa isetyenziswa yodwa, isoloko idityaniswa ne-streptomycin kunye ne-isoniazid, kwaye isetyenziswa kakhulu njengechiza elichasene nesifo sephepha kumgca wesibini.Xa ishushu ukuze ibole ikhupha umsi oyityhefu we-NO, kunye ne-Na2O.Ifanelekile kwi-pulmonary and extrapulmonary tuberculosis ebangelwa yi-Mycobacterium tuberculosis.I-sodium para-aminosalicylate iyasebenza kuphela ngokuchasene ne-mycobacteria kwaye hayi ngokuchasene ne-mycobacteria engekhoyo.Ukunganyangeki kungakhula ngokukhawuleza xa isetyenziswa yodwa, ngoko ke kufuneka idityaniswe namanye amachiza alwa ne-TB.I-Streptomycin kunye ne-isoniazid, xa zidityanisiwe nazo, zinokulibazisa ukukhula kokunganyangeki ngamachiza kwe-Mycobacterium tuberculosis kula machiza mabini.Isetyenziswa kakhulu njengechiza elichasene nesifo sephepha kumgca wesibini.Ingasetyenziselwa i-hyperthyroidism, kwaye ifanelekile kwizigulana ezine-hyperthyroidism kunye nesifo sephepha.Xa i-agent ye-iodine ingasebenzi kwaye ichaphazela ukusebenza, inokuthatyathwa ixesha elifutshane ukudala iimeko zokusebenza.Ukufakwa kwi-intravenous ngokuqhelekileyo kusetyenziswa kwiimeko ezinzima ezifana ne-tuberculous meningitis.

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