I-Sodium Valproate (VPA) CAS 1069-66-5 API Factory High Purity
Ubonelelo ngezoRhwebo loMvelisi ngokucoceka okuPhezulu kunye noMgangatho oZinzileyo
Igama leMichiza: iSodium Valproate (VPA)
CAS: 1069-66-5
Igama leMchiza | I-Sodium Valproate |
Izithethantonye | VPA;Ityuwa yeSodium yeValproic Acid;I-Sodium 2-Propylpentanoate |
Inombolo yeCAS | 1069-66-5 |
Inombolo yeCAT | RF-API14 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C8H15NaO2 |
Ubunzima beMolekyuli | 166.20 |
Indawo yokunyibilika | 300℃ |
Ukuxinana | 1.0803 g/cm3 |
Ukunyibilika kwamanzi | Inyibilika emanzini |
Imeko yokuthumela ngenqanawa | Phantsi koBubushushu be-Ambient |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline oMhlophe okanye oPhantse,, Hygroscopic |
Ukuchongwa | I-Infrared Spectrum Ngokuthelekisa RT Iimpendulo zeTyuwa yeSodium |
Ukunyibilika | Inyibilika kakhulu emanzini, iNyibilika ngokukhululekileyo kwi-Ethanol |
Ubumuncu okanye i-alkalinity | Ngokutsho kwe-EP Criterions |
Ukucaca kunye nombala wesisombululo | Ngokutsho kwe-EP Criterions |
Iintsimbi ezinzima | ≤20ppm |
Iisulfates | ≤200ppm |
I-Chloride | ≤200ppm |
Ilahleko ekomisweni | ≤2.0% |
Nakuphi na Ukungacoceki | ≤0.10% (GC) |
Ukungcola ngokupheleleyo | ≤0.30% (GC) |
Isivavanyi | 98.5%~101.0% (Titration) |
Umgangatho woVavanyo | I-European Pharmacopeia (EP) |
Ukusetyenziswa | I-Active Pharmaceutical ingredient (API) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
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I-Sodium Valproate (i-CAS: i-1069-66-5) i-anticonvulsant kunye ne-arhente esebenzayo yokulawula ukungabikho kokubini kunye nokubanjwa kwe-tonic-clonic ngokubanzi.I-valproic acid ityuwa ye-sodium (i-Sodium Valproate) i-histone deacetylase (i-HDAC) inhibitor, kunye ne-IC50 kuluhlu lwe-0.5 kunye ne-2 mM, iphinda inqanda i-HDAC1 (IC50, 400 μM), kwaye ibangela ukuthotywa kwe-proteasomal ye-HDAC2.Ityuwa ye-sodium ye-Valproic acid yenza i-Notch1 ibonakaliswe kwaye inqande ukwanda kwi-cell cell lung cancer (SCLC) iiseli.I-Sodium Valproate (i-CAS: i-1069-66-5) isetyenziselwa unyango lwe-epilepsy, i-bipolar disorder kunye nokukhusela intloko ye-migraine.
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