I-Sofosbuvir CAS 1190307-88-0 Ubunyulu ≥99.0% (HPLC)
| Igama | Sofosbuvir |
| Izithethantonye | GS-7977;PSI-7977 |
| Inombolo yeCAS | 1190307-88-0 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
| Ifomula yeemolekyuli | I-C22H29FN3O9P |
| Ubunzima beMolekyuli | 529.45 |
| Indawo yokunyibilika | 120.0 ~ 125.0℃ |
| Ukuxinana | 1.41 |
| Ukunyibilika | Inyibilika kwiDMF, DMSO, Ethanol |
| Imeko yokuthumela ngenqanawa | Phantsi koBubushushu be-Ambient |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Imvelaphi | Shanghai, China |
| Beka ubomi kwishelufa | Iinyanga ezingama-36 ukuba zigcinwe ngokufanelekileyo |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Mhlophe ukuya kuMhlophe oMhlophe wePowder |
| Ukuchongwa | I-HPLC;RT |
| Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) |
| EE | ≥99.0% |
| Ilahleko ekomisweni | ≤1.0% |
| Intsalela kwi-Ignition | ≤0.20% |
| Ukungacoceki Okukodwa | ≤0.50% |
| Ukungcola ngokupheleleyo | ≤1.0% |
| Iintsimbi ezinzima | ≤20ppm |
| Izinyibilikisi ezishiyekileyo | Ukuhlangabezana neemfuno zeenkcukacha |
| IMethanol | ≤1500ppm |
| TBME | ≤2500ppm |
| Dichloromethane | ≤720ppm |
| Tetrahydrofuran | ≤720ppm |
| Toluene | ≤60ppm |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | I-Sofosbuvir (CAS: 1190307-88-0) kunyango lwe-Hepatitis C Virus (HCV) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Drum, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma
I-Sofosbuvir (i-CAS: 1190307-88-0) (ebhalwe ngokusemthethweni njenge-PSI-797, GS-7977) yi-prodrug ye-phosphoramidate kunye ne-nucleotide polymerase inhibitor yonyango lwe-virus ye-hepatitis C (HCV) engapheliyo.Kucetyiswa ukuba isetyenziswe ngokudibeneyo namanye amachiza (afana ne-velpatasvir) kunyango lokuqala lwe-HCV genotypes 1, 2, 3, 4, 5, kunye no-6. Isebenza ngokusebenza njenge-nucleotide analog inhibitor, ngokuba ekwaziyo ukuthintela ngokukodwa i-HCV NS5B (iprotein engeyiyo i-5B) exhomekeke kwi-RNA polymerase.
Bhala umyalezo wakho apha kwaye uwuthumele kuthi