Telmisartan CAS 144701-48-4 Ubunyulu > 99.5% (HPLC) API Factory

Inkcazelo emfutshane:

Igama leMichiza: Telmisartan

CAS: 144701-48-4

Ubunyulu: >99.5% (HPLC)

Imbonakalo: Ikristale eMhlophe okanye engekho Mhlophe

I-Angiotensin II Receptor Antagonist

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo lweMichiza yeRuifu yeTelmisartan ePhakathi ngoKucoceka okuPhezulu
I-Telmisartan CAS 144701-48-4
Methyl 2-(p-Tolyl)benzoate CAS 114772-34-8
2-(p-Tolyl)benzoic Acid CAS 7148-03-0
Telmisartan Benzimidazole Acid CAS 152628-03-0
Telmisartan Methyl Ester CAS 528560-93-2
Methyl 2-[4-(Bromomethyl)phenyl]benzoate CAS 114772-38-2
Methyl 4-(Butyrylamino)-3-Methyl-5-Nitrobenzoate CAS 152628-01-8
2-n-Propyl-4-Methyl-6-(1-Methylbenzimidazole-2-yl)benzimidazole CAS 152628-02-9

Iipropati zeMichiza:

Igama leMchiza	I-Telmisartan
Izithethantonye	4'-[[4-Methyl-6-(1-Methyl-1H-Benzimidazol-2-yl)-2-Propyl-1H-Benzimidazol-1-yl]methyl]biphenyl-2-Carboxylic Acid;4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-Benzimidazol]-1'-yl)methyl]-[1,1'-Biphenyl] -2-Carboxylic Acid
Inombolo yeCAS	144701-48-4
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C33H30N4O2
Ubunzima beMolekyuli	514.63
Indawo yokunyibilika	261.0~263.0℃
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo weCrystalline oMhlophe okanye oMhlophe
Ivumba	Uphawu
Ukunyibilika	Inyibilika kancinane kwiMethylene Chloride, Inyibilika kancinane kwiMethanol, iParctically Inyibilika emanzini, inyibilika kwi-1M Solution Hydroxide
Ukuchongwa kwe-IR	Kufuneka ingqinelane ne-RS Infrared Absorption
Ukuchongwa kwe-HPLC	Ixesha lokuGcinwa kweNgxaki eNkulu kufuneka iNxulumane neRS
Ubunyulu / Indlela yokuHlalutya	>99.5% (HPLC)
Ilahleko ekomisweni	<1.00%
Intsalela kwi-Ignition	<0.10%
Izinto ezinxulumeneyo
I-Telmisartan eNxulumene nayo iCompound A	<0.10%
I-Telmisartan Amide	<0.10%
I-Telmisartan eNxulumene nayo iCompound B	<0.10%
I-Telmisartan Diacide	<0.10%
Telmisartan Tert-Butyl Ester	<0.20%
I-Telmisartan Ukungcola okungaziwayo	<0.20%
Ukungcola Okungachazwanga	<0.10%
Ukungcola ngokupheleleyo	<1.00%
Izinyibilikisi ezishiyekileyo
IMethanol	<0.30%
I-Ethanol	<0.50%
I-Methylene Dichloride	<0.06%
n-Hexane	<0.029%
I-Acetic Acid Ethyl Ester	<0.50%
Toluene	<0.089%
I-Acetic Acid	<0.50%
Iintsimbi ezinzima	<10ppm
IArsenic (As)	<1.00ppm
Khokela (Pb)	<1.00ppm
I-Cadmium (Cd)	<1.00ppm
Ubungakanani beNcam	D90 Hayi Ngaphantsi kwe-15μm
Ubuninzi bobuninzi (g/cc)	0.11~0.20
Uxinaniso lweTapped (g/cc)	0.22~0.30
Intsalela yePesticide	Ibi
Ukubalwa kwePleti iyonke	<1000cfu/g
Igwele kunye noMngundo	<100cfu/g
E. Coli	Ibi
Salmonella	Ibi
Umgangatho woVavanyo	uMgangatho woShishino;USP 41 Standard
Ukusetyenziswa	API

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-Telmisartan (i-CAS: 144701-48-4) yi-benzimidazole ephumayo kunye ne-non-peptide angiotensin II receptor antagonist enepropathi ye-antihypertensive.I-Telmisartan ikhetha ukuchasana ne-angiotensin II ebophelela kwi-AT1 subtype receptor, ekwi-vascular smooth muscle kunye ne-adrenal gland.I-antagonism iphumela kwi-vasodilation kwaye inqanda ukuveliswa kwe-aldosterone ye-angiotensin II-mediated, nto leyo ekhokelela ekunciphiseni kwe-sodium kunye namanzi kunye nokunyuka kwe-potassium excretion ekhokelela ekunciphiseni okulandelayo koxinzelelo lwegazi.I-Telmisartan luhlobo olutsha lwamachiza oxinzelelo lwegazi, lusetyenziswa lodwa okanye ludityaniswe nezinye iindidi ze-antihypertensives kunyango loxinzelelo lwegazi.I-Telmisartan yaqala yaqulunqwa yinkampani yaseJamani yamayeza i-Boehringer Ingelheim;yafumana ipatent yaseJamani EP502,314 ngo-1991, yamkelwa okokuqala ukuba ingene kwimarike yaseMelika ngoNovemba ka-1998, emva koko yangena eJamani, kwiiPhilippines, eOstreliya, eBelgium, eBritane, nakwezinye iimarike.