I-Teneligliptin Hydrobromide Teneligliptin HBr CAS 906093-29-6 CAS 906093-29-6 Ubunyulu >99.5% (HPLC) DPP-4 Umzi-mveliso we-Inhibitor
Ubonelelo ngeTeneligliptin Hydrobromide eNxulumene neMiphakathi enoBusulungekileyo obuPhezulu
I-Teneligliptin Hydrobromide CAS 906093-29-6
1-(3-Methyl-1-Phenyl-5-Pyrazolyl)piperazine CAS 401566-79-8
Teneligliptin Hydrobromide Intermediate CAS 401564-36-1
Igama leMchiza | I-Teneligliptin Hydrobromide |
Izithethantonye | I-Teneligliptin HBr |
Inombolo yeCAS | 906093-29-6 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C22H32.5N6OSBr2.5 |
Ubunzima beMolekyuli | 628.86 |
Uphawu | Ruifu Chemical |
Iixesha | Simigangatho | Riziphumo |
Ci-haracteristics | Umgubo oMhlophe okanye oMhlophe | Iyahambelana |
Iukuchongwa | Ngu-IR | Iyahambelana |
Nge-HPLC | Iyahambelana | |
Isiqulatho samanzi (KF) | <6.00% | 3.00% |
Residue onIumlilo | <0.50% | 0.10% |
HlulaMetals (njenge-Pb) | <20ppm | Iyahambelana |
Izinto ezinxulumeneyo | Nakuphi na Ukungcola Okukodwa: <0.10% | 0.05% |
Ukungcola ngokupheleleyo: <0.50% | 0.15% | |
Ubunyulu / Indlela yokuHlalutya | >99.5% (nge-HPLC) | 99.85% |
Isivavanyi | 99.5% ~ 102.0% (Isixhobo esingenamanzi) | 99.90% |
Umgangatho woVavanyo | Umgangatho woShishino | |
Ukuqukumbela | ImvelisoThobeladukuyaEndlwiniUmgangatho. |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-Teneligliptin Hydrobromide (CAS: 906093-29-6) yi-dipeptidyl peptidase-4 (DPP-4) inhibitor esetyenziselwa ukuphatha uhlobo lwe-2 yeswekile.Ikhutshwa nge-excretion, kwaye inesiqingatha sobomi beeyure ezingama-24.2 emzimbeni womntu.I-Teneligliptin yi-DPP-4 inhibitor eyavunywa eJapan ngo-2012 kunyango lwe-type II yeswekile.Yafunyanwa kwaye yaphuhliswa nguMitsubishi Tanabe Pharma phantsi kwegama lorhwebo iTenelia®.Ngokufana nezinye ii-inhibitors ze-DPP-4 ezithengiswayo, i-teneligliptin yanyamezela kakuhle kuzo zonke izifundo kwaye i-QD dosing ivelise isenzo se-inhibitory esihlala ixesha elide ngokuchasene ne-DPP-4 kunye nokunyuka kwamanqanaba asebenzayo e-GLP-1, kunye namazinga aphantsi kakhulu okukhutshelwa kwezintso.