I-Teneligliptin Hydrobromide Intermediate CAS 401564-36-1 Ubunyulu > 99.5% (HPLC) Factory
Ubonelelo ngeTeneligliptin Hydrobromide eNxulumene neMiphakathi enoBusulungekileyo obuPhezulu
I-Teneligliptin Hydrobromide CAS 906093-29-6
1-(3-Methyl-1-Phenyl-5-Pyrazolyl)piperazine CAS 401566-79-8
Teneligliptin Hydrobromide Intermediate CAS 401564-36-1
Igama leMchiza | (2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic acid tert-butyl ester |
Izithethantonye | (S)-tert-Butyl 4-oxo-2-(thiazolidine-3-carbonyl)pyrrolidine-1-carboxylate;I-3-((S) -1-tert-butoxycarbonyl-4-oxo-2-pyrrolidinylcarbonyl) -1,3-thiazolidine;(2S) -4-oxo-2- (1,3-thiazolidin-3-ylcarbonyl)pyrrolidine-1-carboxylate;I-Teneligptin ePhakathi B |
Inombolo yeCAS | 401564-36-1 |
Inombolo yeCAT | RF-1818 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C13H20N2O4S |
Ubunzima beMolekyuli | 300.37 |
Ukuxinana | 1.305 |
Uphawu | Ruifu Chemical |
Into | Umgangatho Wokuhlola | Iziphumo |
Imbonakalo | Emhlophe ukuya kwiCream enemibala eqinile | Vumelana |
Ukuchongwa | I-IR;HPLC RT | Vumelana |
Ilahleko ekomisweni | <1.00% | 0.20% |
Izinto ezinxulumeneyo | Nakuphi na Ukungcola Okukodwa <0.50% | 0.24% |
Ukungcola ngokupheleleyo <0.50% | 0.39% | |
Isivavanyi | 99.5% ~ 102.0% (Kwisiseko esomileyo) | 99.8% |
Ucoceko lwe-Enantiomeric | >99.5% | 99.9% |
Uthuthu lweSulfate | <0.20% | 0.02% |
Umgangatho woVavanyo | Umgangatho woShishino | |
Ukusetyenziswa | Iziphakathi zeTeneligliptin Hydrobromide (CAS: 906093-29-6) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
(2S) -4-Oxo-2- (3-thiazolidinylcarbonyl) -1-pyrrolidinecarboxylic acid tert-butyl ester (CAS: 401564-36-1) yindawo ephakathi esetyenziselwa ukulungiselela i-dipeptidyl peptidase IV (DPP-IV) inhibitor, ephakathi. yeTeneligliptin Hydrobromide (CAS: 906093-29-6).I-Teneligliptin yi-DPP-4 inhibitor eyavunywa eJapan ngo-2012 kunyango lwe-type II yeswekile.Yafunyanwa kwaye yaphuhliswa nguMitsubishi Tanabe Pharma phantsi kwegama lorhwebo iTenelia®.Ngokufana nezinye ii-inhibitors ze-DPP-4 ezithengiswayo, i-Teneligliptin yanyanyezelwa kakuhle kuzo zonke izifundo kwaye idosi ye-QD yavelisa isenzo esithintelayo esihlala ixesha elide ngokuchasene ne-DPP-4 kunye nokunyuka kwamanqanaba asebenzayo e-GLP-1, kunye namazinga aphantsi kakhulu okukhutshelwa kwezintso.