Tenofovir CAS 147127-20-6 Assay 98.0%~102.0% API Anti-HIV Factory
Ubonelelo ngezoRhwebo lwe-Tenofovir oluNxulumene naMaphakathi:
I-Tenofovir CAS: 147127-20-6
I-Tenofovir Disoproxil Fumarate CAS 202138-50-9
I-Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
I-Chloromethyl Isopropyl Carbonate CAS 35180-01-9
I-Diethyl (p-Toluenesulfonyloxymethyl)phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
I-Diethyl (Hydroxymethyl)phosphonate CAS 3084-40-0
Adenine CAS 73-24-5
Igama | I-Tenofovir |
Izithethantonye | (R)-PMPA;(R) -9-(2-Phosphonomethoxypropyl)Adenine |
Inombolo yeCAS | 147127-20-6 |
Inombolo yeCAT | RF-API07 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C9H14N5O4P |
Ubunzima beMolekyuli | 287.22 |
Indawo yokunyibilika | 276.0-280.0℃ |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline oMhlophe okanye ophantse wamhlophe |
Indlela yoVavanyo / yoHlahlelo | 98.0% ~ 102.0% (kwisiseko se-anhydrous) |
Ukunyibilika | I-Soluble kancinane emanzini (0.1g kwi-100ml);Ayinyibiliki kwiMethanol(0.01g kwi-100ml nangaphezulu) |
Ukuchongwa kwe-UV | I-Absorbance malunga ne-261nm |
Ukuchongwa kwe-HPLC | Ixesha lokugcinwa kwencopho yenqununu kwisampula yovavanyo kufuneka lihambelane nelo mgangatho |
I-Sulfate Ash | ≤1.5% |
Amanzi (KF) | ≤3.0% |
Ujikelezo oluKhethekileyo lwe-Optical | -19.0 ° ~ -23.0 ° (ku-25℃ isiseko esingenamanzi) |
Ukungcola kwe-PMPA Monoester | ≤1.5% (HPLC) |
Nakuphi na Ukungacoceki okukokunye okuphezulu | ≤0.5% (HPLC) |
Ukungcola ngokupheleleyo | ≤3.0% (HPLC) |
Ucoceko lwe-Enantiomeric | ≤0.5% (HPLC) |
9-Propenyl Adenine | ≤75ppm (HPLC) |
Umgangatho woVavanyo | Umgangatho woShishino |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma.
I-Tenofovir (i-CAS: 147127-20-6) i-acyclic phosphonate nucleotide analogue kunye ne-reverse-transcriptase inhibitor (NtRTI).Isetyenziswa njenge agent echasene ne-HIV.I-Antiviral.I-Tenofovir disoproxil (Viread) yi-analogue yokuqala ye-nucleotide eyamkelwa yi-FDA yaseMelika ukunyanga usulelo lwe-HIV-1.I-Tenofovir lichiza elisetyenziselwa ukunyanga i-heptatitis B engapheliyo kunye nothintelo kunye nonyango lwe-HIV/AIDS.Ithintela umsebenzi we-HIV reverse transcriptase ngokukhuphisana ne-natural substrate deoxyadenosine 5'-triphosphate, ebangela ukupheliswa kwetsheyini le-DNA.