Trityl Olmesartan Ethyl Ester CAS 144690-33-5 Ubunyulu > 98.5% (HPLC) Factory

Inkcazelo emfutshane:

Igama leMichiza: Trityl Olmesartan Ethyl Ester

CAS: 144690-33-5

Ubunyulu: >98.5% (HPLC)

Imbonakalo: Mhlophe ukuya kwi-Off-White Powder

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com

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Iithegi zeMveliso

Inkcazo:

I-Ruifu Chemical Supply Olmesartan Medoxomil Intermediate with High Quality:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
I-4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
I-Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
I-Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
I-Trityl Olmesartan Acid CAS 761404-85-7
I-N2-Trityl Olmesartan Acid CAS 752179-89-8
I-Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4

Iipropati zeMichiza:

Igama leMchiza	I-Trityl Olmesartan Ethyl Ester
Izithethantonye	I-Olmesartan Ethyl Ester Trityl Ukungcola;Ukungcola kwe-Olmesartan Medoxomil 30;4-(1-Hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(Triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl] -4-yl ]methyl]-1H-Imidazole-5-Carboxylic Acid Ethyl Ester;I-Ethyl 4-(2-hydroxypropan-2-yl)-2-Propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl )methyl)-1H-Imidazole-5-Carboxylate
Inombolo yeCAS	144690-33-5
Inombolo yeCAT	RF-PI1873
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C45H44N6O3
Ubunzima beMolekyuli	716.87
Indawo yokunyibilika	161℃
Ukuxinana	1.18±0.1 g/cm3
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya kwi-Off-White Powder
Ubunyulu / Indlela yokuHlalutya	>98.5% (HPLC)
Isiqulatho samanzi (KF)	<0.50%
Intsalela kwi-Ignition	<0.20%
Ukungcola Ⅰ	<0.10% 4-(1-Hydroxy-1-methylpropyl)-2-propyl-1-{[2'-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]-4-yl ]methyl}-1H-imidazole-5-carboxylic ethyl ester
Ukungcola Ⅱ	<0.10% 4-(1-Methoxy-1-methylethyl)-2-propyl-1-{[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]- 4-yl]methyl}-1H-imidazole-5-carboxylic ethyl ester
Ukungacoceki Ⅲ	<0.50% 4-Isopropenyl-2-propyl-1-{[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]-4-yl]methyl}-1H -imidazole-5-carboxylic ethyl ester
Okunye Ukungcola Okukodwa	<1.00%
Ukungcola ngokupheleleyo	<1.50%
Umgangatho woVavanyo	Umgangatho woShishino

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

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Isicelo:

I-Trityl Olmesartan Ethyl Ester (CAS: 144690-33-5) yinto engcolileyo ye-Olmesartan Medoxomil (CAS: 144689-63-4).I-Olmesartan Medoxomil sisichasi se-angiotensin II receptor esetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu, Isetyenziswa njengechiza elichasene noxinzelelo lwegazi.I-Olmesartan isebenza ngokuthintela ukubophelela kwe-angiotensin II kwi-AT1 receptors kwi-vascular muscle.Ngokuthintela ukubopha endaweni yokwenziwa kwe-angiotensin II, i-Olmesartan inqanda ingxelo engalunganga yolawulo kwi-renin secretion.I-Olmesartan Medoxomil yasungulwa e-US njenge-Benicar@, unyango olulawulwa ngomlomo loxinzelelo lwegazi.I-Olmesartan Medoxomil yenziwa ngokukhawuleza nangokupheleleyo nge-ester hydrolysis kwi-metabolite yayo esebenzayo, i-olmesartan, ngexesha lokufunxa kwiphecana lesisu.