TTBB CAS 124750-51-2 Ubunyulu > 96.0% (HPLC) Irbesartan Intermediate Factory

Inkcazelo emfutshane:

Igama: 5-(4′-Bromomethyl-1,1′-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazole

Izithethantonye: TTBB

I-CAS: 124750-51-2

Ubunyulu: >96.0% (HPLC)

Imbonakalo: Mhlophe ukuya phantse kuMhlophe

Umbindi we-Irbesartan (CAS: 138402-11-6)

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

IRuifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
I-TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1

Iipropati zeMichiza:

Igama leMchiza	5-(4'-Bromomethyl-1,1'-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazole
Izithethantonye	I-TTBB;iBBTT;5-[4'-Bromomethyl-(1,1'-Biphenyl)-2-yl]-1-Triphenylmethyltetrazole;N-(Triphenylmethyl) -5-(4'-Bromomethylbiphenyl-2-yl-)tetrazole;Ukungcola kwe-Olmesartan 12;Losartan Bromo N1-Trityl Ukungcola
Inombolo yeCAS	124750-51-2
Inombolo yeCAT	RF-PI1878
Ubume beStokhwe	Kwi-Stock, iMveliso yeMveliso ye-150MT / Year
Ifomula yeemolekyuli	I-C33H25BrN4
Ubunzima beMolekyuli	557.48
Indawo yokunyibilika	152.0 ~ 155.0℃
Ukuxinana	1.28±0.10 g/cm3
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya Phantse uMhlophe
Ubunyulu / Indlela yokuHlalutya	>96.0% (HPLC)
Ilahleko ekomisweni	<0.50%
Ukungcola A	<2.00% (HPLC) 5-(4-Methyl-1,1-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazole
Ukungcola B	<2.00% 5-(4'.4'-Dibromomethyl-1,1-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazole
I-Infrared Spectrum	Iyahambelana noLwakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi we-Irbesartan (CAS: 138402-11-6);Ukungcola kwe-Olmesartan Medoxomil

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-5-(4'-Bromomethyl-1,1'-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazole (TTBB) (CAS: 124750-51-2) iphakathi kwe-Irbesartan (CAS: 138402-11 -6).I-Irbesartan isetyenziselwa unyango lwe-hypertension, kunye ne-nephropathy yesifo sikashukela kunye ne-serum creatinine ephakamileyo kunye ne-proteinuria (> 300 mg / ngosuku) kwizigulane ezinesifo seswekile se-2 kunye noxinzelelo lwegazi.I-Irbesartan iphinda isetyenziswe njenge-arhente yomgca wesibini kunyango lwe-conges.I-Irbesartan sisichasi se-angiotensin II receptor esetyenziswa ikakhulu kunyango loxinzelelo lwegazi.Yaphuhliswa yiSanofi Research (ngoku iyinxalenye yeSanofi-Aventis).Ithengiswa ngokudibeneyo nguSanofi-Aventis kunye neBristol-Myers Squibb phantsi kwamagama orhwebo Aprovel, Karvea, kunye neAvapro.