IValdecoxib CAS 181695-72-7 Ubunyulu > 99.5% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi weValdecoxib (i-CAS: 181695-72-7) enomgangatho ophezulu.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha lubandakanya inombolo ye-CAS, igama lemveliso, ubuninzi kuthi.Please contact: alvin@ruifuchem.com
| Igama leMchiza | Valdecoxib |
| Izithethantonye | Bextra;SC 65872;Ixabiso;Valz;4-(5-Methyl-3-Phenyl-4-Isooxazolyl)benzenesulfonamide;4-(5-Methyl-3-Phenyl-1,2-Oxazol-4-yl)benzenesulfonamide;4-(5-Methyl-3-Phenylisoxazol-4-yl)benzenesulfonamide |
| Inombolo yeCAS | 181695-72-7 |
| Inombolo yeCAT | RF2833 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | I-C16H14N2O3S |
| Ubunzima beMolekyuli | 314.36 |
| Indawo yokunyibilika | 162.0 ~ 167.0℃ |
| Indawo yokubilisa | 481.2±55.0℃ |
| Ukuxinana | 1.303±0.06 g/cm3 |
| Inovakalelo | Ubushushu Bubuthathaka |
| Ukunyibilika kwamanzi | Ayinyibilikiyo emanzini |
| Ukunyibilika | Inyibilika kwi-Ethanol, iMethanol |
| Ugcino Temp. | Ubushushu beGumbi |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo oMhlophe okanye oMhlophe |
| Ubunyulu / Indlela yokuHlalutya | >99.5% (HPLC) |
| Indawo yokunyibilika | 162.0 ~ 167.0℃ |
| Amanzi (nguKarl Fischer) | <0.50% |
| Intsalela kwi-Ignition | <0.20% |
| Ukungacoceki Okukodwa | <0.30% |
| Ukungcola ngokupheleleyo | <0.50% |
| Iintsimbi ezinzima (njenge Pb) | <20ppm |
| I-Infrared Spectrum | Iyahambelana neSakhiwo |
| NMR Spectrum | Iyahambelana neSakhiwo |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | I-API, i-Second-Generation COX-2 Inhibitor |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
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I-Valdecoxib (i-CAS: i-181695-72-7) isizukulwana sesibini se-COX-2 inhibitor, ephuhliswe njengolandelelwano lwe-celecoxib yonyango yomlomo kanye ngosuku lwe-osteoarthritis, i-rheumatoid arthritis kunye neentlungu zokuya esikhathini.I-Valdecoxib imalunga ne-28,000-iphinda ikhethe ngakumbi kwi-COX-2 yabantu kwakhona kune-COX-1 yabantu.Kwi-ex viva ye-assay yegazi lomntu wonke, ixabiso le-I&O ngokuchasene ne-COX-2 kunye ne-COX-1 ngokulandelanayo 0.89 PM kunye ne-25.4 FM.Kwiimodeli zezilwanyana, i-valdecoxib inomsebenzi obalaseleyo womlomo njenge-anti-inflammatory.Kwiimpuku, i-valdecoxib inhibited carrageenan footpad edema kunye ne-adjuvant-induced arthritis.I-Valdecoxib sisiyobisi esichasene nokudumba (i-NSAID) esibonisa ukudumba, i-analgesic kunye ne-antipyretic kwiimodeli zezilwanyana.I-inhibitor enamandla kwaye ekhethiweyo ye-prostaglandin synthesis ngokuyinhloko ngokuthintela i-COX-2.IValdecoxib isetyenziselwa ukuthomalalisa ezinye iimpawu ezibangelwa sisifo samathambo (rheumatism), ezifana nokudumba, ukudumba, ukuqina, kunye neentlungu zamalungu.I-Valdecoxib ivunyiwe ukukhululeka kweempawu kunye neempawu ze-osteoarthritis kunye ne-rheumatoid arthritis yabantu abadala kunye nonyango lwe-dysmenorrhea yokuqala.I-Valdecoxib ichasene nonyango lwentlungu emva kokuhlinzwa ngokukhawuleza emva kotyando lokuxhunyelelwa kwe-coronary artery bypass.
