Valsartan CAS 137862-53-4 Assay 98.0~102.0% API

Inkcazelo emfutshane:

Igama leMichiza: Valsartan

CAS: 137862-53-4

Imbonakalo: Mhlophe ukuya kwi-Off-White Powder

Uvavanyo: 98.0 ~ 102.0%

Umgangatho ophezulu we-API, iMveliso yoRhwebo.I-Antihypertensive

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-1502674640

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo loMvelisi iValsartan kunye nabaPhakathi abaNxulumeneyo:
Valsartan CAS: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1

Iipropati zeMichiza:

Igama leMchiza	Valsartan
Izithethantonye	N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine
Inombolo yeCAS	137862-53-4
Inombolo yeCAT	RF-API32
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C24H29N5O3
Ubunzima beMolekyuli	435.52
Indawo yokunyibilika	116.0 ~ 117.0℃
Uzinzo	Hygroscopic
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMhlophe okanye oMhlophe;Ayinavumba, iHygroscopic
Ukuchongwa	I-spectrum ye-IR yesampuli ihambelana ne-spectrum yomgangatho wereferensi
Ukuchongwa	Ixesha lokugcinwa kwencopho enkulu kwichromatogram yolungiselelo lovavanyo luhambelana nelo lolungiselelo olusemgangathweni, njengoko lufunyenwe kwi-Assay.
Ukunyibilika	I-Soluble kwi-Methanol kunye ne-Ethanol, iNyibilika kancinane kwi-Ethylacetate, iNyibilika kancinane kwiDichloromethane, i-Soluble in Water
Ukufuma (KF)	≤1.00%
I-Absorbance (420mm)	≤0.02% (λ=420nm, C=0.05g/ml, L=1cm)
Intsalela kwi-Ignition	≤0.10%
Iintsimbi ezinzima	≤10ppm
D-Valsartan	≤1.00% (HPLC)
Izinto eziyeleleneyo (HPLC)
I-Butyryl-Valsartan	≤0.20%
I-Benzyl-Valsartan	≤0.10%
Ukungahlambuluki okungaziwayo okungatshatanga	≤0.10%
Ukungcola ngokupheleleyo	≤0.30% (Ngaphandle kwe-D-Valsartan)
Intsalela yezinyibilikisi (GC)
IMethanol	≤3000ppm
I-Ethyl Acetate	≤5000ppm
N, N-Dimethylformamide	≤880ppm
Toluene	≤890ppm
Ubunyulu / Indlela yokuHlalutya	>99.0% (i-HPLC ibalwa ngesiseko se-anhydrous, i-solvent-free basis)
Umgangatho woVavanyo	I-United States Pharmacopoeia (USP)
Ukusetyenziswa	I-Active Pharmaceutical ingredient (API)

I-Valsartan (CAS: 137862-53-4) Ukuhamba kweNkqubo yeMveliso

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi weValsartan (CAS: 137862-53-4) kunye nomgangatho ophezulu.I-Valsartan yi-nonpeptide angiotensin II AT1 receptor antagonist, i-Antihypertensive, inamandla oxinzelelo lwegazi kunye nophando lwentliziyo.
Iziphumo ze-antihypertensive ze-Valsartan zomelele kunezo ze-enalapril kwaye ifanelekile ukunyanga uxinzelelo lwegazi oluphezulu, oluphakathi ukuya koluphakathi lwe-hypertension, kwaye ngakumbi uxinzelelo lwegazi lwesibini olubangelwa kumonakalo wezintso.Inokunciphisa kakhulu i-proteinuria kwizigulane ezinesifo seswekile okanye imisebenzi eqhelekileyo yesibindi, kwaye inokukhuthaza i-uric acid kunye ne-urinary sodium ukukhusela intso.I-Valsartan ikwafanelekile ekunciphiseni ukusweleka kwentliziyo kwizigulana ezisengozini enkulu (ukusilela kwe-ventricular yasekhohlo okanye ukungasebenzi kakuhle) emva kokuhlaselwa sisifo sentliziyo.