Vidarabine (Ara-A) CAS 5536-17-4 Purity≥99.0% (HPLC) Factory High Quality
Ubonelelo loMvelisi Arabinonucleosides abaPhakathi kunye nobunyulu obuPhezulu
Vidarabine;Ara-A;CAS: 5536-17-4
Arabinofuranosyluracil;Ara-U ;CAS: 3083-77-0
Cytarabine;Ara-C;CAS: 147-94-4
Igama leMchiza | Vidarabine |
Izithethantonye | Ara-A;Arabinoadenosine;I-Adenine 9-β-D-Arabinofuranoside;iVira-A |
Inombolo yeCAS | 5536-17-4 |
Inombolo yeCAT | RF-PI220 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C10H13N5O4 |
Ubunzima beMolekyuli | 267.25 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline oMhlophe okanye oMhlophe |
Ukunyibilika | Ezingenambala zicacile |
Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) |
Imixholo ye-UV | ≥98% (kwisiseko esomileyo) |
Ukujikeleziswa okuthe ngqo [a]D20 | -56.0°~-65.0° (C=1 kwiDMF) |
Adenine | ≤0.50% |
Adenosine | ≤0.50% |
Ara-U | ≤0.50% |
Indawo yokunyibilika | 260.0 ~ 265.0℃ |
Iintsimbi ezinzima | ≤20ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ubushushu boGcino | Gcina ku-0 ~ 8℃ |
Ukusetyenziswa | API;AbaPhakathi bamayeza |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
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I-Vidarabine (i-CAS: i-5536-17-4), ichiza le-antiviral elisebenzayo ngokuchasene ne-herpes simplex kunye ne-varicella zoster virus.I-Vidarabine (i-CAS: i-5536-17-4) i-neurotransmitter esebenza njenge-agonist ekhethiweyo ekhethiweyo kuzo zonke i-adenosine receptor subtypes.I-Vidarabine (i-CAS: 5536-17-4) i-inhibitor ye-A cyclase kunye ne-DNA Polymerase.I-Adenine i-9-beta-D-arabinofuranoside (i-ara-A) yi-nucleoside ye-purine eveliswe ngokwenziwa esetyenziswa kuphando lokubonisa iiseli.Ngokuqhelekileyo isetyenziswe kuphando lwe-anti-viral kunye ne-hepadnaviridae kunye ne-herpes simplex viruses.I-nucleoside ara-A iphazamisa i-viral DNA synthesis, kodwa kuphela kwifom esebenzayo ye-phosphorylated.
I-Vidarabine (i-CAS: i-5536-17-4) i-nucleoside antibiotic eyedwa kwi-Streptomyces antibioticus.Ineempawu ze-antineoplastic kwaye inomsebenzi obanzi ngokuchasene neentsholongwane ze-DNA kwiinkcubeko zeeseli kunye nomsebenzi obalulekileyo we-antiviral ngokuchasene nosulelo olubangelwa ziintsholongwane ezahlukeneyo ezifana neentsholongwane ze-herpes, i-VACCINIA VIRUS kunye ne-varicella zoster virus.I-Vidarabine (CAS: 5536-17-4) iyakwazi ukuthintela i-acyclovir-resistant / TK-deficient mutants ye-HSV kunye ne-VZV, kuba i-phosphorylated kwifom yayo esebenzayo ye-vidarabine-triphosphate nge-cellular kinases kwaye ayixhomekeke ekusebenzeni kwayo yentsholongwane TK.
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