I-Zoledronic Acid Monohydrate CAS 165800-06-6 Ubunyulu ≥99.0% API Factory High Purity
Umenzi onobunyulu obuPhezulu kunye noMgangatho oZinzile
Igama leKhemikhali: I-Zoledronic Acid Monohydrate
CAS: 165800-06-6
I-bisphosphonate enamandla kakhulu kunye ne-activator ye-PKC
Umgangatho ophezulu we-API, iMveliso yoRhwebo
Igama leMchiza | I-Zoledronic Acid Monohydrate |
Inombolo yeCAS | 165800-06-6 |
Inombolo yeCAT | RF-API56 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C5H12N2O8P2 |
Ubunzima beMolekyuli | 290.1 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo omhlophe okanye ophantse ube yiCrystalline |
Ukuchongwa | I-IR Spectrum;HPLC ChromatogramUV-Vis: Kukho i-absorbection ephezulu kwi-210nm |
pH | 2.0~4.0 |
Ukunyibilika | Inyibilika kancinane kwisisombululo se-sodium hydroxide ye-0.1N, i-soluble kancinane emanzini kunye ne-0.1N i-hydrochloric acid, ayinyibiliki kwi-ethanol. |
Ukucaca kunye nombala | Isisombululo kufuneka sicace kwaye singenambala;ukuba i-opalescent, akufuneki i-opalescent ngaphezu kokumiswa kwereferensi 1;ukuba inemibala, ayikho ngaphezulu kwemibala engu-Y2 |
Ukungacoceki Okukodwa | ≤0.50% |
Ukungcola ngokupheleleyo | ≤1.0% |
Ilahleko ekomisweni | 5.0%~8.0% |
I-Chloride | ≤0.02% |
Iphosphate | ≤0.50% |
Phosphite | ≤0.50% |
Iintsimbi ezinzima | ≤10ppm |
Ubunyulu | ≥99.0% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | API |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
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I-Zoledronic acid monohydrate yi-bisphosphonate enamandla kakhulu kunye ne-activator ye-PKC.Zoledronic acid monohydrate yi-heterocyclic bisphosphonate ethathwa njengeyona nto iphezulu kakhulu ye-bisphosphonates yokunciphisa ukunyuka kwamathambo kwaye isetyenziswe kwizifundo ezininzi ze-osteoporosis.I-Zoledronic acid monohydrate yi-inhibitor ye-ASM kunye ne-FDPS kunye ne-activator ye-PKC.I-Zoledronic acid (i-zoledronate) yi-bisphosphonate bone resorption inhibitor, i-inhibitor ye-farnesyl diphosphate (FPP) synthase ebangela ukunyanzeliswa kwe-downstream ye-osteoclast umsebenzi kunye nokunciphisa ukuchithwa kwamathambo kunye nokuguqulwa.Isetyenziselwe ukunyanga i-postmenopausal osteoporosis, isifo sikaPaget, i-hypercalcemia, kunye ne-chemotherapy yomhlaza ukunyanga umonakalo wamathambo obangelwa ngumhlaza oye wasasazeka emathanjeni.
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