1- (1-Benzothiophen-4-yl) piperazine Hydrochloride CAS 913614-18-3 Mimo> 98.0% (HPLC) Brexpiprazole Ile-iṣẹ agbedemeji
Ruifu Kemikali Ipese Brexpiprazole Intermediates
Brexpiprazole CAS 913611-97-9
7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo [b] thiophene CAS 5118-13-8
1- (1-Benzothiophen-4-yl) piperazine Hydrochloride CAS 913614-18-3
7- (4-Chlorobutoxy) quinolin-2 (1H) -ọkan CAS 913613-82-8
4-Chlorobenzo [b] thiophene CAS 66490-33-3
Orukọ Kemikali | 1- (1-Benzothiophen-4-yl) Piperazine Hydrochloride |
Awọn itumọ ọrọ sisọ | Brexpiprazole Intermediate 2;1-Benzo [b] Thien-4-yl-Piperazine Hydrochloride;1-Benzo [b] Thien-4-ylpiperazine Monohydrochloride |
Nọmba CAS | 913614-18-3 |
NỌMBA CAT | RF-PI1034 |
Iṣura Ipo | Ninu Iṣura, Agbara iṣelọpọ 100MT / Ọdun |
Ilana molikula | C12H15ClN2S |
Òṣuwọn Molikula | 254.7789 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun to Pa-White Powder |
Idanimọ | Akoko idaduro ti ayẹwo ni ibamu si ti boṣewa itọkasi |
Mimọ / Analysis Ọna | > 99.0% (HPLC) |
Pipadanu lori Gbigbe | <0.50% |
Omi (KF) | <0.50% |
Aloku lori Iginisonu | <0.20% |
Awọn nkan ti o jọmọ | (HPLC) |
Eyikeyi Olukuluku aimọ | <0.50% |
Lapapọ Awọn Aimọ | <1.00% |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto |
Proton NMR julọ.Oniranran | Ni ibamu si Eto |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji ti Brexpiprazole (CAS: 913611-97-9) |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
1- (1-Benzothiophen-4-yl) piperazine Hydrochloride (CAS: 913614-18-3) jẹ agbedemeji ti Brexpiprazole (CAS: 913611-97-9).Brexpiprazole jẹ iru antipsychotic atypical.O jẹ agonist apa kan olugba dopamine D2.Gẹgẹbi oluyipada iṣẹ ṣiṣe serotonin-dopamine aramada, o le ṣee lo fun itọju schizophrenia, ati fun itọju ajunmọ fun ibanujẹ.O tun le pese ipa ati ifarada lori awọn itọju ajumọṣe ti iṣeto formajor depressive disorder(MDD).Oogun naa ṣe afihan profaili elegbogi alailẹgbẹ kan, ṣiṣe bi agonist apa kan ti serotonin 5-HT1A ati awọn olugba dopamine D2 ati bi antagonist kikun ti 5-HT2A ati awọn olugba noradrenaline α1B/2C, pẹlu isunmọ isọdọkan subnanomolar iru.Oogun naa, eyiti o ni idagbasoke nipasẹ Otsuka ati Lundbeck, ni a fọwọsi ni ọdun 2015 nipasẹ FDA fun itọju schizophrenia ati bi itọju alamọran fun ibanujẹ.