1-Adamantanamine CAS 768-94-5 Mimọ>98.0% (GC)
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Orukọ Kemikali | 1-Adamantanamine |
Awọn itumọ ọrọ sisọ | Amantadine;1-Aminoadamantane;1-Adamantylamine;Adamantan-1-Amin;Tricyclo [3.3.1.13,7]decane-1-amin |
Nọmba CAS | 768-94-5 |
NỌMBA CAT | RF-PI2286 |
Iṣura Ipo | Ni Iṣura, Agbara iṣelọpọ 20 MT / osù |
Ilana molikula | C10H17N |
Òṣuwọn Molikula | 151.25 |
iwuwo | 1,066 g / cm3 |
Ni imọlara | Afẹfẹ Ifamọ |
Solubility (Solubility in) | kẹmika kẹmika;Tiotuka ni Organic solvents.Ailopin ninu Omi |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun to Light Yellow Powder tabi Crystal |
Mimọ / Analysis Ọna | > 98.0% (GC) |
Mimọ / Analysis Ọna | 97.5 ~ 102.5% (Titration nipasẹ HClO4) |
Ojuami Iyo | 207.0 ~ 209.0 ℃ |
Ọrinrin (KF) | <0.50% |
Aloku lori Iginisonu | <0.50% |
Lapapọ Awọn Aimọ | <2.00% |
Solubility ni 1 N HCl | Laini awọ si Irẹwẹsi Yellow, Ko o si Hazy die-die 5% Pass |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto |
Proton NMR julọ.Oniranran | Ni ibamu si Eto |
Igbeyewo Standard | Standard Enterprise |
Lilo | elegbogi Intermediates |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
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1-Adamantanamine, ti a tun mọ ni Amantadine tabi 1-Aminoadamantane tabi 1-Adamantylamine (CAS: 768-94-5) n ṣe bi ayase ni ifaseyin strecker enantioselective ti phosphinoyl imines.O tun wulo fun iṣelọpọ ti awọn itọsẹ adamantane, ie Amantadine Hydrochloride.1-Adamantanamine jẹ ọmọ ẹgbẹ ti kilasi adamantanes ti a lo ninu ile-iṣẹ elegbogi bi antiviral ati oogun antiparkinsonian.Itoju ti Parkinsonism pẹlu apapo Levodopa, awọn oogun anticholinergic, ati amantadine fun awọn esi to dara julọ ju lilo eyikeyi ninu awọn oogun wọnyi lọkọọkan.O jẹ antagonist alailagbara ti olugba NMDA glutamate, eyiti o le mu itusilẹ ti dopamine pọ si ati dina atunbere ti dopamine.Oogun naa le tun ṣe igbega itusilẹ norẹpinẹpirini lati awọn opin nafu ara ni ọpọlọ.O le ṣe itọju dyskinesia ti Arun Pakinsini ati ilọsiwaju dyskinesia lẹhin itọju dopaminergic igba pipẹ.
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