2- (Chloromethyl) -4-Methylquinazoline CAS 109113-72-6 Linagliptin Intermediate Purity ≥99.0% (HPLC)
Linagliptin Ipese Olupese ati Awọn agbedemeji ti o jọmọ:
Linagliptin CAS 668270-12-0
Linagliptin Obi Nucleus Intermediate CAS 853029-57-9
8-Bromo-3-Methylxanthine CAS 93703-24-3
8-Bromo-7- (2-butyn-1-yl)-3-methylxanthine CAS 666816-98-4
2-(Chloromethyl) -4-Methylquinazoline CAS 109113-72-6
(R)-3-(Boc-Amino) piperidine CAS 309956-78-3
(R)-(-)-3-Aminopperidine Dihydrochloride CAS 334618-23-4
1-Bromo-2-Butyne CAS 3355-28-0
Orukọ Kemikali | 2- (Chloromethyl) -4-Methylquinazoline |
Awọn itumọ ọrọ sisọ | Linagliptin agbedemeji A |
Nọmba CAS | 109113-72-6 |
NỌMBA CAT | RF-PI498 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C10H9ClN2 |
Òṣuwọn Molikula | 192.64 |
iwuwo | 1.251 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Bia Yellow to Bia Brown Powder |
Idanimọ A | Apejuwe IR julọ.Oniranran gbọdọ baramu pẹlu irisi iwọnwọn |
Idanimọ B | Akoko idaduro ti opo opo ti ayẹwo gbọdọ ni ibamu si boṣewa |
Solubility | Soluble ni Methylene kiloraidi;Ailopin ninu Omi |
Mimọ / Analysis Ọna | ≥99.0% (HPLC) |
Ojuami Iyo | 60.0 si 65.0 ℃ |
Omi (KF) | ≤0.50% |
Aloku lori Iginisonu | ≤0.50% |
Awọn nkan ti o jọmọ | |
Nikan Aimọ | ≤0.30% |
Lapapọ Awọn Aimọ | ≤1.0% |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji fun Linagliptin (CAS: 668270-12-0) |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
2- (Chloromethyl) -4-Methylquinazoline (CAS: 109113-72-6) ni a lo bi agbedemeji fun igbaradi Linagliptin (CAS: 668270-12-0), ati awọn aimọ rẹ.Linagliptin, ti a ta labẹ orukọ iyasọtọ Tradjenta laarin awọn miiran, jẹ oogun ti a lo lati ṣe itọju iru àtọgbẹ mellitus 2. Ni gbogbogbo ko fẹ ju metformin ati sulfonylureas bi itọju ibẹrẹ.O ti wa ni lilo pọ pẹlu idaraya ati onje.Ko ṣe iṣeduro ni iru àtọgbẹ 1.O ṣiṣẹ nipa jijẹ iṣelọpọ insulin ati idinku iṣelọpọ ti glucagon nipasẹ oronro.Linagliptin ni a fọwọsi fun lilo iṣoogun ni Amẹrika ni ọdun 2011. Linagliptin jẹ agbara ti o lagbara pupọ, oludena dipeptidyl peptidase-4 (DPP-4) yiyan pẹlu IC50 ti 1 nM.