2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Agbedemeji Factory Didara to gaju
Ipese Olupese, Didara to gaju, Iṣelọpọ Iṣowo
Tolvaptan ati Awọn agbedemeji ti o jọmọ:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ọkan CAS 160129-45-3
ìwọ-Toluoyl kiloraidi CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
Orukọ Kemikali | 2-Methyl-4-Nitrobenzoic Acid |
Awọn itumọ ọrọ sisọ | 4-Nitro-o-Toluic Acid;4-Nitro-2-Methylbenzoic Acid |
Nọmba CAS | Ọdun 1975-51-5 |
NỌMBA CAT | RF-PI397 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C8H7NO4 |
Òṣuwọn Molikula | 181.15 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Fere Funfun tabi Bia Yellow Crystal Powder |
1H-NMR | Ni ibamu pẹlu Eto |
Mimọ / Analysis Ọna | ≥98.0% (HPLC) |
Ojuami Iyo | 153.0 ~ 156.0 ℃ |
Ọrinrin (KF) | ≤0.50% |
Aloku lori Iginisonu | ≤0.50% |
Lapapọ Awọn Aimọ | ≤2.0% |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji ti Tolvaptan (CAS 150683-30-0) |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
2-Methyl-4-Nitrobenzoic Acid (CAS 1975-51-5) ni a lo bi agbedemeji elegbogi ni iṣelọpọ ti Tolvaptan (CAS 150683-30-0).Tolvaptan jẹ yiyan, ifigagbaga arginine vasopressin receptor 2 antagonist pẹlu IC50 kan ti 1.28μM fun idinamọ ti akojọpọ platelet ti AVP ti fa.Tolvaptan ni a lo lati ṣe itọju hyponatremia (awọn ipele iṣuu soda ẹjẹ kekere) ti o ni nkan ṣe pẹlu ikuna ọkan iṣọn-alọ ọkan, cirrhosis, ati aarun ti homonu antidiuretic ti ko yẹ (SIADH).Tolvaptan ti fọwọsi nipasẹ Ile-iṣẹ Ounje ati Oògùn AMẸRIKA ni Oṣu Karun ọjọ 19, Ọdun 2009, ati pe o ta nipasẹ Otsuka Pharmaceutical Co. labẹ orukọ iṣowo Samsca.