2-Methyltryptamine CAS 2731-06-8 Mimo>99.0% (HPLC) Panobinostat Intermediate Factory Didara to gaju
Ipese Olupese Pẹlu Didara to gaju, iṣelọpọ Iṣowo
Orukọ Kemikali: 2-Methyltryptamine CAS: 2731-06-8
Orukọ Kemikali | 2-Methyltryptamine |
Awọn itumọ ọrọ sisọ | 2-Methylindole-3-Ethylamine;2- (2-Methyl-1H-indol-3-yl) etanamine;3- (2-Aminoethyl) -2-Methylindole |
Nọmba CAS | 2731-06-8 |
NỌMBA CAT | RF-PI1480 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C11H14N2 |
Òṣuwọn Molikula | 174.25 |
Ojuami Iyo | 106.0 si 110.0 ℃ |
Ojuami farabale | 177℃/1.5mmHg(tan.) |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Brown ri to |
Mimọ / Analysis Ọna | > 99.0% (Agbegbe HPLC) |
1-HNMR | Ni ibamu Pẹlu Be |
Pipadanu lori Gbigbe | <1.00% |
Nikan Aimọ | <0.50% |
Lapapọ Awọn Aimọ | <1.00% |
Awọn irin Heavy (gẹgẹbi Pb) | <20ppm |
Igbeyewo Standard | Standard Enterprise |
Lilo | Awọn agbedemeji elegbogi;Panobinostat Intermediate |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
2-Methyltryptamine (CAS: 2731-06-8) jẹ ohun elo ibẹrẹ bọtini kan ninu iṣelọpọ ti Panobinostat (LBH589) (CAS: 404950-80-7).Panobinostat jẹ oludaniloju to lagbara ti gbogbo awọn deacetylases histone (HDACs), pẹlu awọn iye Ki ti o wa lati 0.6 si 31 nM fun HDAC1-11.Nipasẹ iṣe yii, o nyorisi acetylation ti ọpọlọpọ awọn ọlọjẹ cellular, ti o mu ki imuni ọmọ inu sẹẹli ati apoptosis ninu awọn sẹẹli alakan.Panobinostat jẹ onidalẹkun HDAC akọkọ ti a fọwọsi nipasẹ FDA fun itọju ọpọlọpọ myeloma.Panobinostat ti wa ni tita bi Farydak, ti a lo ni apapo pẹlu Bortezomib (CAS: 179324-69-7) ati Dexamethasone (CAS: 50-02-2) lati ṣe itọju ọpọ myeloma ti o tun pada lẹhin itọju iṣaaju pẹlu Bortezomib ati imunomodulator.