2,3-Dihydrobenzofuran CAS 496-16-2 Ramelteon Intermediate Purity>99.0% (GC)
Asiwaju Olupese ati Olupese, Intermediates ti Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-ọkan CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2- (2,6,7,8-Tetrahydro-1H-Indeno [5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | 2,3-Dihydrobenzofuran |
| Awọn itumọ ọrọ sisọ | Coumaran;2,3-Dihydro-2,3-Benzofuran;2,3-Dihydrobenzo [b]furan;2,3-Dihydro-1-Benzofuran |
| Nọmba CAS | 496-16-2 |
| NỌMBA CAT | RF2884 |
| Iṣura Ipo | Ninu Iṣura, Agbara iṣelọpọ 20 Toonu fun oṣu kan |
| Fọọmu Molecular | C8H8O |
| Òṣuwọn Molikula | 120.15 |
| Ojuami Iyo | -21 ℃ |
| Ojuami farabale | 188.0 ~ 189.0 ℃ (tan.) |
| Oju filaṣi | 66℃ |
| Solubility | Oti: Soluble |
| Akọsilẹ ewu | Irritant |
| TSCA | Bẹẹni |
| HS koodu | 29329995 |
| Ibi ipamọ otutu. | Ididi ni Gbẹ, Yara otutu |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Ko Awọ tabi Omi Yellowish |
| Mimọ / Analysis Ọna | > 99.0% (GC) |
| Omi (nipasẹ Karl Fischer) | <0.50% |
| Ìwọ̀n (20℃) | 1.065 ~ 1.085 |
| Atọka Refractive n20/D | 1.547 ~ 1.551 |
| Aimọ Kanṣoṣo | <0.50% |
| Lapapọ Awọn Aimọ | <1.00% |
| Proton NMR julọ.Oniranran | Ni ibamu si Eto |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Agbedemeji elegbogi ti Ramelteon (CAS: 196597-26-9) |
Package: Igo Fluorinated, 25kg/Drum, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
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DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
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Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
2,3-Dihydrobenzofuran (CAS: 496-16-2) jẹ lilo pupọ ni iṣelọpọ ti awọn agbo ogun tricyclic ati pe o tun jẹ ohun elo aise agbedemeji fun iṣelọpọ diẹ ninu awọn oogun pataki.2,3-Dihydrobenzofuran le ṣee lo bi agbedemeji ti Ramelteon (CAS: 196597-26-9).Ramelteon, ti o ta ọja bi Rozerem nipasẹ Takeda Pharmaceuticals North America, jẹ aṣoju oorun ti o yan ni yiyan si awọn olugba MT1 ati MT2 ni suprachiasmatic nucleus (SCN), dipo dipọ si awọn olugba GABAA, gẹgẹbi pẹlu awọn oogun bii zolpidem.Sibẹsibẹ ko han lati yara ibẹrẹ ti oorun tabi iye oorun ti eniyan n gba.O ti fọwọsi nipasẹ Awọn ipinfunni Ounje ati Oògùn AMẸRIKA (FDA) fun lilo igba pipẹ.Ramelteon ko ṣe afihan eyikeyi abuda ti o ni itẹwọgba si awọn olugba GABAA, eyiti o ni nkan ṣe pẹlu anxiolytic, myorelaxant, ati awọn ipa amnesic.Ko dabi ọpọlọpọ awọn itọju ti insomnia ti o fojusi eka olugba GABA (g-aminobutyric acid), ramelteon jẹ agonist ti olugba melatonin.Ni pataki, o ni yiyan giga fun awọn oriṣi MT1 ati MT2, eyiti o ti ni ipa ninu itọju awọn rhythmu ti circadian, lori olugba MT3 ti o ni iduro fun awọn iṣẹ melatonin miiran.2,3-Dihydrobenzofuran tun wa ni lilo ninu iṣelọpọ ti awọn aṣoju antitumor benzofuran sulfonylureas, HIV protease inhibitor amino acid hydroxyethylenesulfonyl, matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, ati bẹbẹ lọ.
