2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0 Mimọ ≥99.5% (GC) Sitagliptin Phosphate Monohydrate Intermediate
Ipese Sitagliptin Phosphate Monohydrate Awọn agbedemeji ibatan:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R) -3-Amino-4- (2,4,5-Trifluoro-Phenyl) -Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Agbedemeji CAS 486460-21-3
Orukọ Kemikali | 2,4,5-Trifluorophenylacetic Acid |
Nọmba CAS | 209995-38-0 |
NỌMBA CAT | RF-PI1191 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C8H5F3O2 |
Òṣuwọn Molikula | 190.12 |
Ojuami Iyo | 121.0 si 125.0 ℃ |
Solubility | Tiotuka ni kẹmika |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun to Pa-White Powder |
Mimọ / Analysis Ọna | ≥99.5% (GC) |
Ọrinrin (KF) | ≤0.50% |
Aloku lori Igniton | ≤0.50% |
Lapapọ Awọn Aimọ | ≤0.50% |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
2,4,5-Trifluorophenylacetic Acid (CAS: 209995-38-0) jẹ agbedemeji Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9).Sitagliptin Phosphate (STG) ni a lo lati ṣe itọju DM iru 2 nitori pe o mu iṣakoso glycemic pọ si nipa jijẹ awọn ipele ti awọn homonu incretin ti nṣiṣe lọwọ, GLP-1 (peptide-1) ati GIP (glucose-based insulinotropic peptide).Iṣiṣẹ ti awọn incretin wọnyi ni awọn sẹẹli β-pancreatic fa awọn ipele ti o pọ si ti adenosine monophosphate cyclic (cAMP) ati kalisiomu intracellular, pẹlu yomijade insulini ti o gbẹkẹle glukosi ti o tẹle (2).Oogun hypoglycemic yii jẹ ti kilasi tuntun ti a pe ni dipeptidyl peptidase IV inhibitors.STG ti fọwọsi nipasẹ FDA ni ọdun 2006.