3-[3- (Trifluoromethyl) phenyl] -1-Propanol CAS 78573-45-2 Cinacalcet Hydrochloride Intermediate Purity>99.0% (HPLC)
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ti 3-[3- (Trifluoromethyl) phenyl] -1-Propanol (CAS: 78573-45-2) pẹlu didara to gaju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, kekere ati awọn iwọn olopobobo ti o wa.Ra 3-[3- (Trifluoromethyl) phenyl] -1-Propanol,Please contact: alvin@ruifuchem.com
Orukọ Kemikali | 3-[3- (Trifluoromethyl) phenyl] -1-Propanol |
Awọn itumọ ọrọ sisọ | 3- [3- (Trifluoromethyl) phenyl] propanol;3- (3'-Trifluoromethylphenyl) propanol;3- (3- (Trifluoromethyl) phenyl) propan-1-ol;3- (Trifluoromethyl) propanol benzene |
Aimọ | USP Cinacalcet Ijọṣepọ Agbo E |
Iṣura Ipo | Ninu Iṣura, Iwọn Iṣowo |
Nọmba CAS | 78573-45-2 |
Fọọmu Molecular | C10H11F3O |
Òṣuwọn Molikula | 204,19 g / mol |
Ojuami farabale | 60℃/1.13mmHg(tan.) |
Oju filaṣi | 105 ℃ |
Ibi ipamọ otutu. | Itura & Ibi Gbẹ |
COA & MSDS | Wa |
Ẹka | elegbogi Intermediates |
Brand | Ruifu Kemikali |
Awọn nkan | Ayewo Standards | Esi |
Ifarahan | Ailokun to Light Yellow Liquid | Ibamu |
Omi nipa Karl Fischer | <0.50% | 0.07% |
Mimọ / Analysis Ọna | > 99.0% (HPLC) | 99.60% |
Atọka Refractive n20/D | 1.462 ~ 1.466 | Ibamu |
Ìwọ̀n (20℃) | 1.212 ~ 1.216 | Ibamu |
Infurarẹẹdi julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
1 H NMR julọ.Oniranran | Ni ibamu pẹlu Eto | Ibamu |
Ipari | Ọja naa ti ni idanwo & ni ibamu pẹlu awọn pato | |
Ohun elo | Agbedemeji ti Cinacalcet Hydrochloride (CAS: 364782-34-3) |
Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti o ni edidi ni itura ati ile-itọju gbigbẹ kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
3- [3- (Trifluoromethyl) phenyl] -1-Propanol (CAS: 78573-45-2) jẹ agbedemeji ninu iṣelọpọ ti Cinacalcet Hydrochloride (CAS: 364782-34-3).Cinacalcet jẹ titẹsi akọkọ ni kilasi tuntun ti awọn aṣoju iwosan ti a pe ni calcimimetics.O ti ṣe ifilọlẹ bi itọju ẹnu fun hyperparathyroidism Atẹle (SHPT) ni awọn alaisan ti o ni arun kidinrin onibaje lori dialysis ati fun hypercalcemia ni awọn alaisan ti o ni carcinoma parathyroid.SHPT ni nkan ṣe pẹlu iṣelọpọ homonu parathyroid (PTH) ti o pọ si, eyiti o fa nipasẹ awọn ipele omi ara kekere ti kalisiomu ti o waye lati ikuna ti kidinrin lati ko phosphorous kuro ninu ara ati ailagbara rẹ lati gbe awọn iwọn Vitamin D ti o to. pẹlu iwuri ti iṣẹ-ṣiṣe osteoclastic, isọdọtun egungun cortical ati fibrosis ọra inu.PTH yomijade ti wa ni nipataki ofin nipa awọn kalisiomu-sensing receptor (CaR), eyi ti o ti wa ni be lori dada ti awọn olori cell ti awọn parathyroid ẹṣẹ.Calcimimetics sopọ mọ CaR ati mu ifamọ ti CaR pọ si kalisiomu extracellular, nitorinaa muu mu ṣiṣẹ ni awọn ipele abẹlẹ ti kalisiomu omi ara.Bi abajade, niwaju awọn aṣoju wọnyi, awọn ipele kekere ti kalisiomu ti o wa ninu awọn alaisan ti o ni ikuna kidirin ni anfani lati ṣe ipa ipanilara lori yomijade PTH.Carcinoma Parathyroid tun ni nkan ṣe pẹlu awọn ipele PTH ti o ga, eyiti o jẹ idari nipasẹ iṣẹ-ṣiṣe ẹṣẹ parathyroid adase ati lẹhinna ja si hypercalcemia.Botilẹjẹpe isọdọtun iṣẹ abẹ jẹ itọju ailera akọkọ fun atọju hypercalcemia ni awọn alaisan parathyroid carcinoma, calcimimetics nfunni ni yiyan ti kii ṣe iṣẹ abẹ fun awọn alaisan ti o ni parathyroidectomy ti o kuna, carcinoma metastatic parathyroid carcinoma, tabi eewu iṣẹ-abẹ giga.