4-[(1-Pyrrolidinylsulfonyl)methyl] aniline CAS 334981-10-1 Mimọ>99.0% (HPLC) Almotriptan Aniline Precursor Factory
Ipese Kemikali Ruifu Almotriptan Malate Intermediates:
Almotriptan Malate CAS 181183-52-8
1-((4-Hydrazinylbenzyl) sulfonyl) pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)methyl] aniline CAS 334981-10-1
1-[(4-Nitrophenylmethyl) sulfonyl] pyrrolidine CAS 340041-91-0
4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9
Orukọ Kemikali | 4-[(1-Pyrrolidinylsulfonyl) methyl] aniline |
Awọn itumọ ọrọ sisọ | 1- [(4-Aminobenzyl) sulfonyl] pyrrolidine;Almotriptan Aniline Precursor |
Nọmba CAS | 334981-10-1 |
NỌMBA CAT | RF-PI1948 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C11H16N2O2S |
Òṣuwọn Molikula | 240.32 |
Ojuami Iyo | 170.0 si 176.0 ℃ |
iwuwo | 1.31 |
Solubility | Die-die Soluble ni Toluene |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun si Irẹwẹsi Yellow Crystalline Powder |
Mimọ / Analysis Ọna | > 99.0% (HPLC) |
Pipadanu lori Gbigbe | <0.50% |
Aloku lori Iginisonu | <0.50% |
Max Nikan Aimọ | <0.50% |
Lapapọ Awọn Aimọ | <1.00% |
Awọn irin Heavy | <20ppm |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto |
NMR | Ni ibamu si Eto |
Igbeyewo Standard | Standard Enterprise |
Lilo | Almotriptan Aniline Precursor |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
![1](https://a395.goodao.net/uploads/15.jpg)
![](https://a395.goodao.net/uploads/23.jpg)
4- [(1-Pyrrolidinylsulfonyl) methyl] aniline (CAS: 334981-10-1) jẹ agbedemeji ni igbaradi Almotriptan Malate (CAS: 181183-52-8), Almotriptan Aniline Precursor.Almotriptan Malate jẹ iru oogun triptan eyiti o le ṣee lo fun itọju awọn efori migraine.Almotriptan jẹ ti ẹya oogun ti awọn agonists olugba serotonin ti o yan.Almotriptan ni ibaramu giga ati pato fun awọn olugba serotonin 5-HT, eyiti o yori si vascoconstriction ti ohun elo ẹjẹ ọpọlọ ati ni ipa lori atunkọ sisan ẹjẹ.Awọn ipa wọnyi da awọn ifihan agbara irora duro lati firanṣẹ si ọpọlọ, ati didimu siwaju itusilẹ ti awọn nkan adayeba ti o fa irora, ọgbun ati awọn ami aisan migraine miiran.Sibẹsibẹ, Almotriptan ko ṣe idiwọ ikọlu migraine.Almotriptan, ti o ta ọja ni ọdun 2000, ni wiwa oralbioa ti o ga julọ laarin gbogbo awọn triptans.Almotriptan jẹ metabolized nipasẹ mejeeji MAO-A ati CYP3A4, nitorinaa ni profaili awọn ipa ẹgbẹ ti o dara julọ nigbati a bawe pẹlu Sumatriptan.