4- (4-Pyridinyl) thiazole-2-thiol CAS 77168-63-9 Mimọ ≥99.0% Ceftaroline Fosamil Cephalosporin Intermediate
Ipese Olupese, Iwa-mimọ giga, Iṣelọpọ Iṣowo
Orukọ Kemikali: 4- (4-Pyridinyl) thiazole-2-thiol
CAS: 77168-63-9
Orukọ Kemikali | 4- (4-Pyridinyl) thiazole-2-thiol |
Nọmba CAS | 77168-63-9 |
NỌMBA CAT | RF-PI558 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C8H6N2S2 |
Òṣuwọn Molikula | 194.28 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Pa-White to Bia Yellow Powder |
Ayẹwo | ≥99.0% |
Pipadanu lori Gbigbe | ≤0.50% |
Awọn nkan ti o jọmọ | |
Nikan Max.Aimọ | ≤0.50% |
Lapapọ Awọn Aimọ | ≤1.0% |
Igbeyewo Standard | Standard Enterprise |
Lilo | Aarin ti Ceftaroline Fosamil (TAK-599), itọsẹ Cephalosporin kan |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
4- (4-Pyridinyl) thiazole-2-thiol (CAS: 77168-63-9) ni a lo gẹgẹbi agbedemeji Ceftaroline Fosamil (TAK-599).Ceftaroline Fosamil jẹ oluranlowo antibacterial cephalosporin ti o fọwọsi ni Amẹrika ni Oṣu Kẹwa Ọdun 2010 fun itọju IV ti awọ-ara kokoro-arun nla ati awọn àkóràn ara-ara (ABSSSI) ati pneumonia kokoro-arun ti agbegbe (CABP).Ceftaroline Fosamil ni omi-soluble, N-phosphono prodrug of ceftaroline (T-91825), gbooro-spekitiriumu, oluranlowo bactericidal pẹlu iṣẹ-ṣiṣe ti o lagbara lodi si awọn igara Staphylococcus aureus (MRSA) ti o ni methiccillin, S. pneumonia ti o ni ọpọlọpọ awọn oògùn, ati giramu ti o wọpọ. -odi oganisimu.Ceftaroline sopọ mọ PBP2a bakannaa awọn PBP miiran pẹlu isunmọ giga ati, bi abajade, ṣe idaduro iṣẹ ṣiṣe to lagbara.Ceftaroline ṣe afihan iṣẹ-ṣiṣe lodi si ọpọlọpọ awọn pathogens ti o dara giramu, pẹlu β-lactam-ni ifaragba ati -sooro S. aureus, vancomycin-sooro S. aureus, ati awọn fọọmu ti o ni ifaragba ati ti S. pneumoniae ṣugbọn o ni iṣẹ-ṣiṣe ti ko lagbara lodi si Enterococcus sp.Iṣẹ-ṣiṣe antibacterial-gram-negative ti ceftaroline wa ni opin nipataki si awọn aarun atẹgun bii Moraxella catarrhalis ati Haemophilus influenzae.