4-Benzyl-2-Hydroxymorpholin-3-ọkan CAS 287930-73-8 Mimọ>99.0% (HPLC) Ile-iṣẹ Agbedemeji Aperepitant

Apejuwe kukuru:

Orukọ: 4-Benzyl-2-Hydroxymorpholin-3-ọkan

CAS: 287930-73-8

Mimọ:> 99.0% (HPLC)

Irisi: Funfun si Paa-White Crystal Powder

Agbedemeji ti Aprepitant (CAS: 170729-80-3) Antiemetic

Didara to gaju, iṣelọpọ Iṣowo

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Apejuwe:

Asiwaju olupese ati olupese
Awọn agbedemeji ti Aprepitant (CAS: 170729-80-3)
4-Benzyl-2-Hydroxymorpholin-3-ọkan CAS 287930-73-8
(R) -1- [3,5-Bis (trifluoromethyl) phenyl] ethanol CAS 127852-28-2
Please contact: alvin@ruifuchem.com

Kemikali Properties:

Orukọ Kemikali 4-Benzyl-2-Hydroxymorpholin-3-ọkan
Awọn itumọ ọrọ sisọ 4-Benzyl-2-Hydroxy-Morpholin-3-ọkan;2-Hydroxy-4- (Phenylmethyl) -3-Morpholinone;Ibanujẹ Alaimọ 48;Fosaprepitant Aimọ 23;Agbedemeji agbedemeji Ⅱ
Nọmba CAS 287930-73-8
NỌMBA CAT RF2660
Iṣura Ipo Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Fọọmu Molecular C11H13NO3
Òṣuwọn Molikula 207.23
Ojuami Iyo 134.0 si 138.0 ℃
Ojuami farabale 441,7 ± 45,0 ℃
iwuwo 1,292 ± 0,06 g / cm3
Solubility ninu Omi DMSO (Diẹ), kẹmika (Diẹ, Kikan)
Brand Ruifu Kemikali

Awọn pato:

Nkan Awọn pato
Ifarahan Funfun to Pa-White Crystal Powder
Mimọ / Analysis Ọna > 99.0% (HPLC)
Ojuami Iyo 134.0 si 138.0 ℃
Omi (nipasẹ Karl Fischer) <0.50%
Aloku lori Iginisonu <0.20%
Lapapọ Awọn Aimọ <1.00%
Proton NMR julọ.Oniranran Ni ibamu si Eto
Igbeyewo Standard Standard Enterprise
Lilo Agbedemeji ti Aprepitant (CAS: 170729-80-3) Oogun Antiemetic

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

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Ohun elo:

4-Benzyl-2-Hydroxymorpholin-3-ọkan (CAS: 287930-73-8), jẹ agbedemeji ti Aprepitant (CAS: 170729-80-3), ti a lo bi awọn oogun antiemetic.Aprepitant jẹ antagonist olugba neurokinin-1 (NK-1) ati pe o jẹ ti awọn aṣoju itọju ti eebi lakoko kimoterapi ti akàn.Ni akọkọ ni aṣeyọri nipasẹ Merck Company (German).Ni Oṣu Kẹta ọdun 2003, Ile-iṣẹ Ounje ati Oògùn AMẸRIKA fọwọsi rẹ fun lilo ninu itọju eebi kimoterapi.Ọja yii ni isunmọ yiyan giga si awọn eniyan lakoko ti o ni ibatan kekere si serotonin, dopamine ati ibaramu olugba glucocorticoid.Aprepitant, nigba ti a ba ni idapo pẹlu awọn oludena olugba 5-HT3 (gẹgẹbi ondansetron hydrochloride) ati corticosteroid dexamethasone, le tun din cisplatin-induced ńlá ati (tabi) idaduro idaduro.Lilo oogun yii nikan le ni ipa idena diẹ.

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