Olaparib Intermediate CAS 763114-26-7 Purity ≥98.5% Factory
Iwa mimọ giga, iṣelọpọ Iṣowo
Olaparib ati Awọn agbedemeji ti o jọmọ:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl) benzoic acid CAS 763114-26-7
1- (Cyclopropylcarbonyl) piperazine Hydrochloride CAS 1021298-67-8
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
| Orukọ Kemikali | 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl) benzoic acid |
| Awọn itumọ ọrọ sisọ | 2-Fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl] benzoic acid |
| Nọmba CAS | 763114-26-7 |
| NỌMBA CAT | RF-PI450 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C16H11FN2O3 |
| Òṣuwọn Molikula | 298.27 |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Yellow to Pa-White Powder |
| Ayẹwo | ≥98.5% |
| Ọrinrin (KF) | ≤0.50% |
| Lapapọ Awọn Aimọ | ≤1.5% |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Agbedemeji ti Olaparib (CAS: 763113-22-0) |
Package: Igo, apo apamọwọ Aluminiomu, Ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl) benzoic acid (CAS: 763114-26-7) jẹ agbedemeji ti a lo ninu iṣelọpọ ti Olaparib (CAS: 763113-22). -0).Olaparib, ti o ta nipasẹ AstraZeneca labẹ orukọ iyasọtọ Lynparza, ni a fọwọsi ni AMẸRIKA ni Oṣu Kejila ọdun 2014 gẹgẹbi ibi-afẹde kan, itọju aṣoju-ọkan fun itọju germline BRCA-mediated to ti ni ilọsiwaju ovarian cancer.Olaparib, ti ipilẹṣẹ nipasẹ KuDOS pharmaceuticals ati nigbamii nipasẹ AstraZeneca , Awọn iṣẹ bi poly ADP ribose polymerase inhibitor ati pe a ti fọwọsi ni pato fun awọn alaisan ti o ti gba awọn itọju mẹta tabi diẹ sii ti chemotherapy.Ninu awọn idanwo ile-iwosan, oogun naa pẹ ni ilọsiwaju-ọfẹ iwalaaye fun awọn alaisan ti o ni ifaramọ Pilatnomu ti o nwaye loorekoore akàn ovarian serous.Olaparib tun wa lọwọlọwọ ni ọpọlọpọ awọn ipele iwadii fun itọju igbaya, ikun, prostate, pancreatic ati akàn ẹdọfóró sẹẹli ti kii ṣe kekere.
