4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Purity>98.5% (HPLC) Lenvatinib Mesylate Agbedemeji Factory Aworan Ifihan

4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Mimọ>98.5% (HPLC) Lenvatinib Mesylate Agbedemeji Factory

Apejuwe kukuru:

Orukọ: 4-Chloro-7-Methoxyquinoline-6-Carboxamide

CAS: 417721-36-9

Mimọ:> 98.5% (HPLC)

Irisi: Pa-White to Light Yellow Powder

Agbedemeji ti Lenvatinib Mesylate CAS 857890-39-2

Didara to gaju, iṣelọpọ Iṣowo

E-Mail: alvin@ruifuchem.com

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Jẹmọ Products

ọja Tags

Apejuwe:

Ipese Kemikali Ruifu Lenvatinib Mesylate Intermediates Pẹlu Iwa mimọ to gaju
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1- (2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5- (Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dion CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Kemikali Properties:

Orukọ Kemikali	4-Chloro-7-Methoxyquinoline-6-Carboxamide
Awọn itumọ ọrọ sisọ	4-Chloro-7-Methoxy-6-Quinolinecarboxamide;Lenvatinib Aimọ 12;Lenvatinib Iwa Aimọ B;Lenvatinib Aimọ LFS-B
Nọmba CAS	417721-36-9
NỌMBA CAT	RF-PI1971
Iṣura Ipo	Ninu Iṣura, Agbara iṣelọpọ 50MT / Ọdun
Ilana molikula	C11H9ClN2O2
Òṣuwọn Molikula	236.65
Ojuami Iyo	> 205 ℃ (oṣu kejila)
iwuwo	1.380 ± 0.060 g / cm3
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Pa-White to Light Yellow Powder
Mimọ / Analysis Ọna	> 98.5% (HPLC)
Pipadanu lori Gbigbe	<0.50%
Aloku lori Iginisonu	<0.50%
Lapapọ Awọn Aimọ	<1.50%
Proton NMR julọ.Oniranran	Ni ibamu si Eto
Igbeyewo Standard	Standard Enterprise
Lilo	Agbedemeji ti Lenvatinib Mesylate (CAS: 857890-39-2)

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

Awọn anfani:

FAQ:

Ohun elo:

4-Chloro-7-Methoxyquinoline-6-Carboxamide (CAS: 417721-36-9) ti wa ni lilo julọ bi agbedemeji ti Lenvatinib Mesylate (CAS: 857890-39-2).Idagbasoke nipasẹ Eisai Inc., lenvatinib mesylate jẹ olutọpa ti iṣan ti iṣan ti iṣan ti iṣan (VEGF) ti o ni iṣẹ-ṣiṣe lodi si VEGF subtypes 1, 2, ati 3 ati pe FDA fọwọsi ni 2015 fun itọju ti akàn tairodu ti o yatọ ti o jẹ boya ni agbegbe. loorekoore, metastatic, tabi ilọsiwaju ati pe ko dahun si itọju iodine ipanilara.Ni Oṣu Karun ọdun 2016, FDA fọwọsi oogun naa gẹgẹbi apapọ itọju ailera pẹlu everolimus fun itọju ti carcinoma sẹẹli kidirin to ti ni ilọsiwaju.Nitoripe VEGF (ati fibroblast idagba ifosiwewe awọn olugba, ti a mọ ni FGFRs) ni a ro pe o ṣe ipa kan ninu awọn ipa ọna ifihan agbara ẹjẹ, VEGF2R ati FGFR idinamọ ni a ro pe awọn ilana ti o wa lẹhin ipa akọkọ ti lenvatinib mesylate, eyiti o jẹ haipatensonu.