5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 Dapagliflozin Ile-iṣẹ agbedemeji
Ipese Olupese, Iwa-mimọ giga, Iṣelọpọ Iṣowo
Dapagliflozin (CAS: 461432-26-8) Awọn agbedemeji ti o jọmọ:
5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
| Orukọ Kemikali | 5-Bromo-2-Chlorobenzoic Acid |
| Awọn itumọ ọrọ sisọ | 2-Chloro-5-Bromobenzoic Acid |
| Nọmba CAS | 21739-92-4 |
| NỌMBA CAT | RF-PI439 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C7H4BrClO2 |
| Òṣuwọn Molikula | 235.46 |
| Ojuami Iyo | 154.0 si 156.0 ℃ (tan.) |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Pa-White to Light Yellow Powder |
| Ayẹwo | ≥99.0% |
| Omi (KF) | ≤0.50% |
| Aloku lori Iginisonu | ≤0.30% |
| 2-Chlorobenzoic Acid | ≤0.30% |
| 2-Chloro-3-Bromobenzoic Acid | ≤0.30% |
| Lapapọ Awọn Aimọ | ≤1.0% |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Aarin ti Dapagliflozin (CAS: 461432-26-8), iru àtọgbẹ II. |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
5-Bromo-2-Chlorobenzoic Acid (CAS: 21739-92-4) ni a lo bi ohun elo ti o bẹrẹ ni iṣelọpọ ti Dapagliflozin (CAS: 461432-26-8), oludena iṣuu soda-glucose cotransporter-2 ti o yan ti o dinku kidirin. glukosi reabsorption ati pe a lo lati tọju awọn alaisan ti o ni àtọgbẹ iru II.Dapagliflozin jẹ oludena SGLT-2 (SLC5A2) ti o lagbara ati yiyan pẹlu EC50 ti 1.1 nM.O ni agbara to dara kọja awọn membran sẹẹli Caco-2 ati pe o jẹ sobusitireti fun P-glycoprotein (P-gp).Dapagliflozin jẹ ifọwọsi ni ọdun 2012 nipasẹ FDA.
