5-Methylisoxazole-4-Carboxylic Acid CAS 42831-50-5 Leflunomide Intermediate Purity>99.0% (HPLC)

Apejuwe kukuru:

Orukọ Kemikali: 5-Methylisoxazole-4-Carboxylic Acid

Synonyms: 5-Methyl-4-Isoxazolecarboxylic Acid

CAS: 42831-50-5

Mimọ:> 99.0% (HPLC)

Funfun si Pale Crystalline Powder, Odorless

Agbedemeji ti Leflunomide (CAS: 75706-12-6)

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Apejuwe:

Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ ti 5-Methylisoxazole-4-Carboxylic Acid (CAS: 42831-50-5) pẹlu didara to gaju.Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati titobi nla ti o wa.Ra 5-Methylisoxazole-4-Carboxylic Acid,Please contact: alvin@ruifuchem.com

Kemikali Properties:

Orukọ Kemikali	5-Methylisoxazole-4-Carboxylic Acid
Awọn itumọ ọrọ sisọ	5-Methyl-4-Isoxazolecarboxylic Acid
Aimọ	Leflunomide EP Aimọ D/ Leflunomide BP Aimọ D
Iṣura Ipo	Ninu Iṣura, Iwọn Iṣowo
Nọmba CAS	42831-50-5
Fọọmu Molecular	C5H5NO3
Òṣuwọn Molikula	127,10 g / mol
Ojuami Iyo	145.0 si 149.0 ℃ (tan.)
iwuwo	1.348 ± 0,06 g / cm3
Ibi ipamọ otutu.	Itura & Ibi Gbẹ (2 ~ 8℃)
COA & MSDS	Wa
Brand	Ruifu Kemikali

Awọn pato:

Awọn nkan	Ayewo Standards	Esi
Ifarahan	Funfun si Pale Crystalline Powder, Odorless	Ibamu
Ojuami Iyo	145.0 si 149.0 ℃	147.8 ~ 148,5 ℃
Pipadanu lori Gbigbe	≤0.50%	0.13%
Aloku lori Iginisonu	≤0.10%	0.04%
Awọn Irin Eru (Pb)	≤0.002%	<0.002%
3-Methyl Isomeric yellow	≤0.20%	<0.20%
Mimọ / Analysis Ọna	> 99.0% (HPLC)	99.74%
Infurarẹẹdi julọ.Oniranran	Ni ibamu si Eto	Ibamu
1 H NMR julọ.Oniranran	Ni ibamu si Eto	Ibamu
Ipari	Ọja naa ti ni idanwo & ni ibamu pẹlu awọn pato ti a fun
Nlo	Agbedemeji elegbogi ti Leflunomide (CAS: 75706-12-6)

Package/Ipamọ/Gbigbe:

Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Tọju ni wiwọ titi eiyan.Fipamọ sinu itura, gbigbẹ (2 ~ 8℃) ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.

Awọn anfani:

Agbara to to: Awọn ohun elo to ati awọn onimọ-ẹrọ

Iṣẹ Ọjọgbọn: Iṣẹ rira iduro kan

OEM Package: Aṣa package ati aami wa

Ifijiṣẹ Yara: Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta

Ipese Idurosinsin: Ṣetọju ọja iṣura ti o tọ

Atilẹyin imọ-ẹrọ: Ojutu imọ-ẹrọ wa

Iṣẹ Iṣọkan Aṣa: Larin lati giramu si kilos

Didara to gaju: Ṣeto eto idaniloju didara pipe

FAQ:

Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.

Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.

Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.

DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl

Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.

Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.

MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.

Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.

Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.

Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.

Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.

Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.

42831-50-5 - Ewu ati Aabo:

Awọn koodu ewu
R36 / 37/38 - Irritating si oju, eto atẹgun ati awọ ara.
R37 / 38 - Irritating si eto atẹgun ati awọ ara.
R36 - irritating si awọn oju
R10 - flammable
Apejuwe Abo
S22 - Maṣe simi eruku.
S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun.
S36/37/39 - Wọ aṣọ aabo to dara, awọn ibọwọ ati aabo oju / oju.
S36 - Wọ aṣọ aabo to dara.
S16 - Jeki kuro lati awọn orisun ti iginisonu.
WGK Germany 3
HS koodu 2917399090
Ewu Class IRRITANT

Ohun elo:

5-Methylisoxazole-4-Carboxylic Acid (CAS: 42831-50-5) jẹ agbedemeji fun iṣelọpọ ti Leflunomide (CAS: 75706-12-6).Leflunomide jẹ iru awọn oogun ajẹsara isoxazole pẹlu iṣẹ ṣiṣe anti-proliferative, elegbogi ode oni ṣe iyasọtọ ọja yii bi antipyretic, analgesic ati awọn oogun egboogi-iredodo.Ọja yii le ṣe iyipada ni iyara si awọn metabolites ti nṣiṣe lọwọ ati ṣe ipa nipasẹ ẹdọ ati cytoplasm oporoku ati awọn microsomes, awọn oniwe-;akọkọ siseto ni nigba DNA kolaginni, inhibiting a bọtini enzymu-DHODH (DHODH) aṣayan iṣẹ-ṣiṣe, ki awọn nucleotides laarin awọn B lymphocyte ti wa ni depleted, o fopin si awọn biosynthesis ti DNA ati RNA, awọn sẹẹli ko le tẹ s alakoso, ati be ko le proliferate, Abajade ni awọn ipa anti-rheumatic, o dara fun itọju awọn agbalagba pẹlu arthritis rheumatoid ti nṣiṣe lọwọ, spondylitis ankylosing, o le fa fifalẹ iparun egungun, dinku awọn aami aisan ati awọn ami.Ni afikun, leflunomide tun le ṣe idiwọ iṣẹ ṣiṣe ti tyrosine kinase, nitorinaa ṣe idiwọ itankale sẹẹli T, sẹẹli B ati awọn sẹẹli ti kii ṣe ajẹsara, ṣugbọn o tun le, nipasẹ idinamọ biosynthesis ti cyclooxygenase-2 (COX2), ṣe idiwọ iṣelọpọ prostaglandin ati ṣiṣẹ egboogi-egbogi. awọn ipa iredodo ati dena awọn sẹẹli mast ati itusilẹ histamini basophils.Nigbati a ba lo ọja yii ni awọn alaisan gbigbe ara eniyan, atunṣe iwọn lilo nira, o jẹ pataki julọ lati tọju arthritis rheumatoid ati awọn aarun autoimmune miiran.