6-Aminohexanoic Acid CAS 60-32-2 (ε-aminocaproic Acid) Assay 98.5 ~ 100.5% Factory
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti 6-Aminohexanoic Acid (ε-aminocaproic Acid) (CAS: 60-32-2) pẹlu didara to gaju.A le pese ifijiṣẹ agbaye, kekere ati titobi pupọ ti o wa.Ti o ba nifẹ si 6-Aminohexanoic Acid,Please contact: alvin@ruifuchem.com
Orukọ Kemikali | 6-Aminohexanoic Acid |
Awọn itumọ ọrọ sisọ | Aminocaproic acid;ε-Acp;6-aminocaproic acid;(6-)ε- Aminocaproic Acid;Aminocaproic acid;epsilon-Aminocaproic Acid;EACA;ACS;H-6-Aca-OH;Hemocaprol;6-Amino-n-Hexanoic Acid;ε-Amino-n-Hexanoic Acid;Amicar |
Iṣura Ipo | Ninu Iṣura, Agbara iṣelọpọ 500 Toonu fun Ọdun |
Nọmba CAS | 60-32-2 |
Fọọmu Molecular | C6H13NO2 |
Òṣuwọn Molikula | 131.18 |
Ojuami Iyo | Nipa 204 ℃ Pẹlu Iparun |
iwuwo | 1,042 g / cm3 |
Ni imọlara | Afẹfẹ Ifamọ |
Òórùn | Alaini oorun |
Omi Solubility | Tiotuka Larọwọto ninu Omi, O fẹrẹ jẹ akoyawo |
Solubility | Soluble Larọwọto ninu Omi ati ni Glacial Acetic Acid, Pupọ Tiotuka Ni Methanol pupọ, Aifọwọyi Ni adaṣe ni Chloroform, Ethanol, Ether |
Ibi ipamọ otutu. | Ididi ni Gbẹ, Itaja ni Yara otutu |
COA & MSDS | Wa |
Brand | Ruifu Kemikali |
Awọn koodu ewu | Xi - Irritant |
Awọn Gbólóhùn Ewu | 36/37/38 - Irritating si oju, eto atẹgun ati awọ ara. |
Apejuwe Abo | S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun.S36 - Wọ aṣọ aabo to dara. |
WGK Germany | 2 |
RTECS | MO6300000 |
TSCA | Bẹẹni |
HS koodu | 2922491990 |
Oloro | LD50 ninu awọn eku (g/kg): 7.0 ip;~ 3.3 iv (Hallesy) |
Awọn nkan | Ayewo Standards | Esi |
Ifarahan | Awọn kirisita funfun tabi Crystalline Powder;Lenu Kikoro die | Ni ibamu |
Idanimọ | Infurarẹẹdi Absorption julọ.Oniranran | Ni ibamu |
Ipo Solusan (Gbigbepo) | Ko o ati Alailowaya ≥98.0% | 98.6% |
Kloride (Cl) | ≤0.020% | <0.020% |
Sulfate (SO4) | ≤0.020% | <0.020% |
Ammonium (NH4) | ≤0.020% | <0.020% |
Irin (Fe) | ≤30ppm | <30ppm |
Awọn Irin Eru (Pb) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
UV Absorbance | A a1≤0.10 (287nm) a2≤0.03 (450nm) | a1: 0.030 a2: 0.006 |
B a1≤0.15 (287nm) a2≤0.03 (450nm) | a1: 0.121 a2: 0.012 | |
Awọn amino acids miiran | Chromatographically Ko ṣe iwari | Ni ibamu |
Omi (nipasẹ Karl Fischer) | ≤0.50% | 0.20% |
Ajẹkù lori Iginisonu (Sulfated) | ≤0.10% | 0.05% |
Ayẹwo | 98.5 si 100.5% (lori ipilẹ Anhydrous) | 99.8% |
Ninhydrin-Rere Awọn nkan | ≤0.50% | Ni ibamu |
Iye pH | 7.0 si 8.0 (1.0g ni 10ml ti H2O) | 7.76 |
Ipari | Pade pẹlu Standard ti AJI97, USP35, EP8.0, BP2005 | |
Awọn Lilo akọkọ | Aṣoju Anti-Fibrinolytic;Aṣoju Hemostatic |
6-Aminohexanoic Acid (ε-aminocaproic Acid) (CAS: 60-32-2) Ọna Idanwo AJI97
Aminocaproic Acid, nigba ti a ṣe iṣiro lori ipilẹ anhydrous, ko kere ju 98.5 ninu ogorun ko si ju 100.5 ogorun ti Aminocaproic Acid (C6H13NO2).
Apejuwe: Awọn kirisita funfun tabi lulú kirisita, itọwo kikorò die.
Tiotuka larọwọto ninu omi ati ni glacial acetic acid, die-die tiotuka ni kẹmika, Oba insoluble ni ethanol.
Solubility (H2O, g/100g): Larọwọto tiotuka ninu omi
Idanimọ: Ṣe afiwe irisi gbigba infurarẹẹdi ti ayẹwo pẹlu ti boṣewa nipasẹ ọna disiki bromide potasiomu.
Awọn pato:
Ipo Solusan (Igbejade): 0.5g ni 10ml ti H2O, spectrophotometer, 430nm, 10mm cell sisanra.
Chloride (Cl): 0.7g, A-1, atunṣe: 0.40ml ti 0.01mol/L HCl
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), atunṣe: 0.50ml ti 0.005mol/L H2SO4
Iron (Fe): 0.5g, Ref: 1.5ml of Iron Std.(0.01mg/ml)
Awọn irin Eru (Pb): 2.0g, (1), pH=7, atunṣe: 2.0ml ti Pb Std.(0.01mg/ml)
Arsenic (As2O3): 2.0g, (1), atunṣe: 2.0ml ti As2O3 Std.
Amino Acids miiran: Ayẹwo idanwo: 100μg, B-1-a, iṣakoso;ε-Acp 0.6μg
Omi: 500mg, methanol: ethyleneglycol (1: 2) fun Ọna Karl Fischer, A, fun awọn iṣẹju 15.
Ajẹkù lori Ignition (Sulfated): Idanwo AJI 13
Ayẹwo: Ayẹwo ti a ṣe iṣiro lori ipilẹ anhydrous, 130mg, (1), 3ml ti formic acid, 50ml ti glacial acetic acid, 0.1mol/L HCLO4 1ml=13.117mg C6H13NO2
pH: 1.0g ni 10ml ti H2O
Iwọn ibi ipamọ ti a ṣe iṣeduro ati ipo: Awọn apoti wiwu ti a tọju ni iwọn otutu yara ti iṣakoso (ọdun 2).
6-Aminohexanoic Acid (ε-aminocaproic Acid) (CAS: 60-32-2) Ọna Idanwo USP35
Aminocaproic Acid ko kere ju 98.5 ninu ogorun ati pe ko ju 101.5 ogorun ti C6H13NO2, iṣiro lori ipilẹ anhydrous.
Iṣakojọpọ ati ibi ipamọ-Fipamọ sinu awọn apoti ti o muna.Fipamọ ni iwọn otutu yara.
Awọn ajohunše Itọkasi USP <11>-
USP Aminocaproic Acid RS
Idanimọ, Gbigba infurarẹẹdi <197K>.
Omi, Ọna I <921>: ko ju 0.5%.
Aloku lori ina <281>: ko ju 0.1%.
Awọn irin ti o wuwo, Ọna II <231>: 0.002%.
Ayẹwo-
Solusan A-Gbigbe lọ si 0.55 g ti iṣuu soda 1-heptanesulfonate si 1000-mL volumetric flask, tu sinu ati dilute pẹlu omi si iwọn didun, ati dapọ.
Ipele alagbeka-Gbigbe 10 g ti fosifeti potasiomu monobasic si beaker 1000-mL, tu ni 300 milimita ti Solusan A, fi 250 milimita kẹmika ti kẹmika, atẹle pẹlu 300 milimita miiran ti Solusan A, ati dapọ.Ṣatunṣe adalu pẹlu phosphoric acid si pH ti 2.2.Gbe gbogbo adalu lọ si 1000-mL volumetric flask, dilute pẹlu Solusan A si iwọn didun, ati dapọ.Àlẹmọ ati degas.Ṣe awọn atunṣe ti o ba jẹ dandan (wo Ibaramu Eto labẹ Chromatography <621>).
Ojutu boṣewa inu-Mura ojutu kan ti methionine ninu omi ti o ni 1.25 miligiramu fun milimita kan.
Igbaradi Boṣewa-Tu opoiye iwuwo deede ti USP Aminocaproic Acid RS ninu omi lati gba ojutu Iṣura kan ti o ni ifọkansi ti a mọ ti 12.5 miligiramu fun milimita kan.Gbigbe 5.0 milimita ti ojutu Iṣura si ọpọn iwọn didun 100-mL, ṣafikun 2.0 milimita ti ojutu boṣewa inu, dilute pẹlu omi si iwọn didun, ati dapọ.
Assay igbaradi-Gbigbe lọ si iwọn deedee opoiye ti 1.25 g ti Aminocaproic Acid si 100-mL ọpọn igo volumetric kan, tu sinu ati dilute pẹlu omi si iwọn didun, ati dapọ.Gbigbe 5.0 milimita ti ojutu yii si 100-mL volumetric flask, ṣafikun 2.0mL ti ojutu boṣewa inu, dilute pẹlu omi si iwọn didun, ati dapọ.
Eto Chromatographic (wo Chromatography <621>) -Kromatograph olomi ti ni ipese pẹlu aṣawari 210-nm ati iwe 4.6-mm × 15-cm ti o ni iṣakojọpọ L1 ati ti o tọju ni 30°.Iwọn sisan jẹ nipa 0.7 milimita fun iṣẹju kan.Chromatograph the Standard igbaradi, ati ki o ṣe igbasilẹ awọn idahun ti o ga julọ bi a ti ṣe itọsọna fun Ilana: awọn akoko idaduro ibatan jẹ nipa 0.76 fun aminocaproic acid ati 1.0 fun methionine;ipinnu, R, laarin aminocaproic acid ati methionine ko kere ju 2.0;ati iyapa boṣewa ojulumo fun awọn abẹrẹ ẹda ko ju 2.0%.
Ilana-Lọtọ ara awọn iwọn didun dogba (nipa 20 µL) ti igbaradi Standard ati igbaradi Assay sinu chromatograph, ati gba igbaradi Assay lati yọkuro fun ko din igba meji akoko idaduro aminocaproic acid.Ṣe igbasilẹ awọn chromatograms, ki o wọn gbogbo awọn idahun ti o ga julọ.Ṣe iṣiro iye, ni g, ti C6H13NO2 ni apakan Aminocaproic Acid ti o mu nipasẹ agbekalẹ:
2C(RU/RS)
ninu eyiti C jẹ ifọkansi, ni miligiramu fun milimita kan, ti USP Aminocaproic Acid RS ni igbaradi Standard;ati RU ati RS jẹ awọn ipin ti idahun tente oke aminocaproic acid si idahun ti o ga julọ ti inu ti a gba lati igbaradi Assay ati igbaradi Standard, lẹsẹsẹ.
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6-Aminohexanoic Acid (ε-aminocaproic Acid; 6-Aminocaproic Acid) (CAS: 60-32-2) (Orukọ ami iyasọtọ: Amicar) jẹ iru itọsẹ sintetiki ti lysine.Niwọn bi o ti jẹ afọwọṣe ti amino acid lysine, o le ṣe bi oludena fun awọn enzymu ti o nilo lati sopọ mọ aloku lysine yẹn pato, fun apẹẹrẹ enzymu proteolytic gẹgẹbi plasmin, eyiti o jẹ iduro fun fibrinolysis.Nitorinaa, o ni iṣẹ ṣiṣe anti-fibrinolytic.O tun ṣe idiwọ imuṣiṣẹ ti plasminogen ni ifigagbaga, nitorinaa idinku iyipada ti plasminogen si plasmin.Da lori ohun-ini yii, o le ṣee lo fun itọju ẹjẹ nla nitori iṣẹ ṣiṣe fibrinolytic ti o ga ni ọpọlọpọ awọn ipo ile-iwosan.O tun le ṣe itọkasi nipasẹ FDA fun idena ti isun ẹjẹ loorekoore ni awọn alaisan ti hyphema ọgbẹ.O tun le ṣe bi prophylactic lodi si arun ti iṣan nitori ipa idiwọ rẹ lori dida lipoprotein eyiti o jẹ ifosiwewe eewu ti arun ti iṣan.Aminobenzoic Acid Gel, Aminocaproic Acid Abẹrẹ, Aminocaproic Acid Solusan Oral, Aminobenzoic Acid Topical Solusan.
Ohun elo
6-Aminohexanoic Acid ni a lo bi reagent biokemika.6-Aminocaproic Acid ni a lo ninu iṣelọpọ Organic.Gẹgẹbi oluranlowo anti-fibrinolytic.Ti a lo bi oluranlowo hemostatic.6-aminocaproic acid ni ipa pataki lori diẹ ninu awọn ẹjẹ ti o lagbara ti o fa nipasẹ iṣẹ-ṣiṣe fibrinolytic ti o pọ sii.O dara fun didan tabi ẹjẹ agbegbe lakoko ọpọlọpọ awọn iṣẹ abẹ.6-aminocaproic acid tun lo fun hemoptysis, ẹjẹ inu ikun ati ẹjẹ ẹjẹ ni awọn obstetrics ati gynecology.6-Aminocaproic Acid ṣiṣẹ nipa idinamọ eto fibrinolytic.Ni akọkọ ti a lo fun iṣọn-ẹjẹ ti o ṣẹlẹ nipasẹ iṣẹ ṣiṣe plasmin ti o ga, gẹgẹbi awọn obstetrics ati ẹjẹ ẹjẹ gynecology, ẹjẹ ẹjẹ lẹhin pirositeti, ẹdọ, pancreas, ẹdọfóró ati awọn iṣẹ visceral miiran.Oogun inu ibẹrẹ tabi oogun iṣaaju le dinku eefin inu iṣan ati dinku iwọn gbigbe ẹjẹ.
6-Aminocaproic Acid jẹ oogun egboogi-fibrinolytic ti o ni iru ilana kemikali kan si lysine.O le ṣe idiwọ isokan ti plasminogen si fibrin ati idilọwọ imuṣiṣẹ rẹ, nitorinaa dena fibrinolysis ati iyọrisi hemostasis.Aminocaproic acid jẹ monoaminocarboxylic acid, eyiti o le ṣe idiwọ iyipada ti plasminogen sinu plasmin ati asopọ rẹ si fibrin.Fun ẹjẹ ti o lagbara ti o fa nipasẹ hyperfibrinolysis ti o fa nipasẹ imuṣiṣẹ pọ si ti plasminogen, le ni ipa itọju ailera.