6-O-Methylguanine CAS 20535-83-5 Ile-iṣẹ Agbedemeji Nelzarabine
Ipese Pẹlu Iwa mimọ giga, iṣelọpọ Iṣowo
Orukọ Kemikali: 6-O-Methylguanine
CAS: 20535-83-5
| Orukọ Kemikali | 6-Eyin-Methylguanine |
| Awọn itumọ ọrọ sisọ | 2-Amino-6-Methoxypurine |
| Nọmba CAS | 20535-83-5 |
| NỌMBA CAT | RF-PI509 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C6H7N5O |
| Òṣuwọn Molikula | 165.16 |
| Ojuami Iyo | > 300 ℃ (tan.) |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Pa-White Crystalline Powder |
| Aseyori / Analysis Ọna | ≥98.5% (HPLC) |
| Pipadanu lori Gbigbe | ≤0.50% |
| Aloku lori Iginisonu | ≤0.50% |
| Lapapọ Awọn Aimọ | ≤1.5% |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Agbedemeji ti Nelzarabine (CAS: 121032-29-9), T-ALL & T-LBL |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
6-O-Methylguanine (CAS: 20535-83-5) le ṣee lo bi agbedemeji ni iṣelọpọ ti Nelzarabine (CAS: 121032-29-9).Nelarabine jẹ oogun oogun fun analogue deoxyguanosine-9-beta-D-arabinofuranosyl guanine (ara-G).Nelarabine demethylates ni ipa ti adenosine deaminase (ADA) ati ki o yipada si ara-G.Nelarabine ti kọkọ ni aṣeyọri nipasẹ GlaxoSmithKline.Ni Oṣu Kẹwa Ọjọ 28, Ọdun 2005 labẹ ifọwọsi ti Awọn ipinfunni Ounje ati Oògùn AMẸRIKA, o di oogun tuntun fun iwosan T-cell ńlá lymphoblastic leukemia (T-ALL) ati T-Cells lymphoblasticlymphoma (T-LBL) eyiti o jẹ sooro si o kere ju. awọn oriṣi meji ti awọn ilana itọju chemotherapy tabi ifasẹyin lẹhin itọju akọkọ.Oogun tuntun yii ṣe atokọ ni ifowosi ni Amẹrika ni ọdun 2006.
