![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ọkan CAS 160129-45-3 Tolvaptan Agbedemeji Aworan Ifihan](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3.jpg)
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ọkan CAS 160129-45-3 Tolvaptan Intermediate
Ipese Olupese, Didara to gaju, Iṣelọpọ Iṣowo
Tolvaptan ati Awọn agbedemeji ti o jọmọ:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ọkan CAS 160129-45-3
ìwọ-Toluoyl kiloraidi CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Orukọ Kemikali | 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ọkan |
| Awọn itumọ ọrọ sisọ | 7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ọkan;7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-ọkan |
| Nọmba CAS | 160129-45-3 |
| NỌMBA CAT | RF-PI395 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C10H10ClNO |
| Òṣuwọn Molikula | 195.65 |
| Ojuami Iyo | 103.0 si 107.0 ℃ |
| Solubility | Tiotuka ni kẹmika |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Ina Green to Light Yellow Powder |
| Awọn ọna Idanimọ | NMR, HPLC |
| Mimọ / Analysis Ọna | ≥99.0% (HPLC) |
| Pipadanu lori Gbigbe | ≤1.0% |
| Aloku lori Iginisonu | ≤0.50% |
| Eyikeyi Nikan Aimọ | ≤0.50% |
| Lapapọ Awọn Aimọ | ≤1.0% |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Aarin ti Tolvaptan (CAS 150683-30-0), itọju Hyponatremia. |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
7-Chloro-1,2,3,4-tetrahydrobenzo [b] azepin-5-one (CAS 160129-45-3) jẹ agbedemeji ninu iṣelọpọ ti Tolvaptan (CAS 150683-30-0).Tolvaptan jẹ yiyan, ifigagbaga ẹnu ti nṣiṣe lọwọ nonpeptide arginine vasopressin V2 antagonist olugba olugba pẹlu IC50 kan ti 1.28µM fun idinamọ ti akojọpọ platelet ti AVP ṣe.Tolvaptan ni a lo lati tọju hyponatremia ti o ni nkan ṣe pẹlu ikuna ọkan iṣọn-alọ ọkan, cirrhosis, ati aarun ti homonu antidiuretic ti ko yẹ.Tolvaptan tun wa ninu awọn idanwo ile-iwosan iyara-yara fun arun kidinrin polycystic.Itoju pẹlu Tolvaptan fa iyara ati idaduro iwuwo ara idinku nigbakan pẹlu awọn alekun ninu iṣelọpọ ito, ilọsiwaju ati/tabi ṣe deede iṣuu soda ni awọn alaisan hyponatremic, dinku awọn ami ati awọn aami aiṣan ti iṣubu ati mu ongbẹ pọ si.
![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ọkan CAS 160129-45-3 Tolvaptan Intermediate](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3-300x300.jpg)
