7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 Purity>99.0% (HPLC) Afatinib Dimaleate Agbedemeji Factory Afihan Aworan

7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 Purity>99.0% (HPLC) Afatinib Dimaleate Intermediate Factory

Apejuwe kukuru:

Orukọ: 7-Chloro-6-Nitro-4-Hydroxyquinazoline

CAS: 53449-14-2

Mimọ:> 99.0% (HPLC)

Irisi: Imọlẹ Yellow si Light Brown Powder

Agbedemeji ti Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

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Jẹmọ Products

ọja Tags

Apejuwe:

Ruifu Kemikali Ipese Intermediates of Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4 (1H) -ọkan CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S) -N4- (3-Chloro-4-Fluorophenyl) -7- ((Tetrahydrofuran-3-yl) oxy) quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N- (3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy) quinazolin-4-AmineCAS 314771-88-5

Kemikali Properties:

Orukọ Kemikali	7-Chloro-6-Nitro-4-Hydroxyquinazoline
Awọn itumọ ọrọ sisọ	7-Chloro-4-Hydroxy-6-Nitroquinazoline;7-Chloro-6-Nitro-4-Quinazolinol;7-Chloro-6-Nitro-4-Quinazolinone;7-Chloro-6-Nitro-4 (3H) - Quinazolinone;7-Chloro-6-Nitro-3,4-Dihydroquinazolin-4-ọkan;7-Chloro-6-Nitroquinazolin-4 (3H) -ọkan
Nọmba CAS	53449-14-2
NỌMBA CAT	RF-PI2030
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Ilana molikula	C8H4ClN3O3
Òṣuwọn Molikula	225.59
Ifamọ	Ooru kókó
Solubility	Tiotuka diẹ ni Dimethylformamide
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Ina Yellow to Light Brown lulú
Idanimọ (HPLC)	Akoko idaduro ti Ayẹwo yẹ ki o baamu pẹlu Standard
Mimọ / Analysis Ọna	> 99.0% (HPLC)
Ojuami Iyo	300.0 ~ 303.0 ℃
Akoonu Omi (KF)	<0.50%
Aloku lori Iginisonu	<0.30%
Aimọ́ 1	<0.50% (7-Chloro-4-Hydroxyquinazoline CAS: 31374-18-2)
Aimọ́ 2	<0.50% (5,7-Dichloro-4[1H]quinazolinone)
Aimọ́ 3	<1.00% (7-Chloro-8-Nitro-4[1H]quinazolinone)
Miiran Single aimọ	<0.20%
Lapapọ Awọn Aimọ	<1.00%
Awọn irin Heavy (gẹgẹbi Pb)	<20ppm
Infurarẹẹdi julọ.Oniranran	Ni ibamu si Eto
Proton NMR julọ.Oniranran	Proton NMR julọ.Oniranran
Igbeyewo Standard	Standard Enterprise
Lilo	Intermediate of Afatinib, Afatinib Dimaleate

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

Awọn anfani:

FAQ:

Ohun elo:

7-Chloro-6-Nitro-4-Hydroxyquinazoline (CAS: 53449-14-2) jẹ agbedemeji ti Afatinib Dimaleate (CAS: 850140-73-7).Afatinib jẹ idile ErbB ti ko le yipada ti awọn oludena ti o dinku gbigbe alaye ati dina awọn ipa ọna pataki ti o ni ipa ninu idagbasoke sẹẹli alakan ati pipin.Nitori ẹrọ gbigbe alaye ti idile ErbB le ṣe okunfa nipasẹ ọpọlọpọ awọn homodimers ati heterodimers, idinamọ nigbakanna ti awọn ọmọ ẹgbẹ ẹbi ErbB pupọ (bii EGFR, HER2, ErbB3 ati ErbB4) le ṣe idiwọ gbigbejade alaye isale.Afatinib ni a lo lati ṣe itọju iru akàn ẹdọfóró kan (akàn ẹdọfóró sẹẹli ti kii ṣe kekere) ti o ti tan si awọn ẹya miiran ti ara.O jẹ ti kilasi awọn oogun ti a mọ si awọn inhibitors kinase.O ṣiṣẹ nipa idinku tabi didaduro idagba ti awọn sẹẹli alakan.O sopọ mọ amuaradagba kan (igbasilẹ epidermal-EGFR) ni diẹ ninu awọn èèmọ.