7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity
Ipese Olupese Irinotecan ati Awọn agbedemeji ti o jọmọ:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Orukọ Kemikali | 7-Ethyl-10-Hydroxycamptothecin |
| Awọn itumọ ọrọ sisọ | SN-38 |
| Nọmba CAS | 86639-52-3 |
| NỌMBA CAT | RF-PI242 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C22H20N2O5 |
| Òṣuwọn Molikula | 392.41 |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Light Yellowish White kirisita lulú |
| Idanimọ (IR, UV) | (1) Ultraviolet ray gbigba julọ.Oniranran ibamu pẹlu awọn ibeere (2) Infurarẹẹdi ray gbigba spekitiriumu concordant pẹlu itọkasi boṣewa julọ.Oniranran yoo ni ibamu pẹlu awọn idanwo ti a fọwọsi |
| Ojuami Iyo | 228.0 ~ 235.0 ℃ |
| Awọn nkan ti o jọmọ | ≤1.5% |
| 10-Hydroxycamptothecin | ≤0.30% |
| 7-Cthylcamptothecin | ≤0.70% |
| O pọju aimọ aimọ | ≤0.50% |
| Pipadanu lori Gbigbe | ≤1.0% |
| Awọn Irin Eru | ≤10ppm |
| Aloku lori Iginisonu | ≤0.10% |
| wípé Solusan | Ko o |
| Ayẹwo | ≥98.0% (HPLC) |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Pharmaceutical Intermediate of Irinotecan |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) pẹlu didara to gaju.7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) jẹ metabolite ti nṣiṣe lọwọ ti Topoisomerase I inhibitor Irinotecan.SN-38 (NK012) ṣe idiwọ DNA ati iṣelọpọ RNA pẹlu IC50s ti 0.077 ati 1.3 μM, lẹsẹsẹ.7-Ethyl-10-Hydroxycamptothecin (SN-38), ni awọn ti nṣiṣe lọwọ metabolite ti Irinotecan, a semisynthetic itọsẹ ti camptothecin, a quinoline-orisun alkaloid ri ninu epo igi ti Chinese camptotheca igi ati awọn Asia nothapodytes igi.Botilẹjẹpe 7-Ethyl-10-Hydroxycamptothecin jẹ to awọn akoko 1,000 diẹ sii ni agbara ju Irinotecan, ko ti yipada si oludije oogun ti o le yanju nitori pe ko ṣee ṣe.Lọwọlọwọ o ti wa labẹ awọn idanwo ile-iwosan ni apapọ pẹlu awọn ẹya miiran eyiti o le gba laaye nikẹhin lati ni imunadoko bi oogun antineoplastic.
