7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1 Mimọ>99.0% (GC) Agomelatine Intermediate
Olupese asiwaju ati Olupese ti Agomelatine Intermediates
Agomelatine CAS 138112-76-2
7-Methoxy-1-Tetralone CAS 6836-19-7
7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
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Orukọ Kemikali | 7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester |
Awọn itumọ ọrọ sisọ | Ethyl 2- (7-Methoxynaphthalen-1-yl) acetate |
Nọmba CAS | 6836-21-1 |
NỌMBA CAT | RF2687 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C15H16O3 |
Òṣuwọn Molikula | 244.29 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Ina Yellow Sihin Liquid |
Mimọ / Analysis Ọna | > 99.0% (GC) |
Omi (nipasẹ Karl Fischer) | <0.50% |
Awọn nkan ti o jọmọ | <1.00% |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto |
NMR julọ.Oniranran | Ni ibamu si Eto |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji elegbogi ti Agomelatine (CAS: 138112-76-2) |
Package: Florinated Igo, 25kg/Barrel, tabi gẹgẹbi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
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DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
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7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester (CAS: 6836-21-1) jẹ agbedemeji sintetiki Organic ti o wulo, o le lo bi agbedemeji elegbogi ti Agomelatine (CAS: 138112-76-2).Agomelatine, eyiti o jẹ idagbasoke nipasẹ ile-iṣẹ Servier Faranse, jẹ awọn olugba melatonin akọkọ ni agbaye MT1 ati MT2 agonist kilasi ti awọn antidepressants.O kan si awọn itọju ti agbalagba alaisan pẹlu àìdá depressive.Agomelatine jẹ oogun apakokoro.Agomelatine jẹ agonist ti melatonin (MT) awọn olugba ati itọsẹ ti melatonin.O sopọ mọ awọn olugba MT1 ati MT2 (Kis = 0.14 ati 0.41 nM, lẹsẹsẹ) ati pe o ni iye EC50 kan ti 0.1 nM ninu idanwo abuda [35S] GTPγS nipa lilo awọn sẹẹli CHO ti n ṣalaye awọn olugba MT2.O ti pin si bi norẹpinẹpirini-dopamine disinhibitor (NDDI) nitori atako rẹ ti olugba 5-HT2C.Iṣiṣẹ ti awọn olugba 5-HT2C nipasẹ serotonin ṣe idiwọ dopamine ati itusilẹ norẹpinẹpirini.