Afatinib Dimaleate Intermediate CAS 314771-88-5 Purity>99.0% (HPLC) Factory
Ruifu Kemikali Ipese Intermediates of Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4 (1H) -ọkan CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S) -N4- (3-Chloro-4-Fluorophenyl) -7- ((Tetrahydrofuran-3-yl) oxy) quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N- (3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy) quinazolin-4-AmineCAS 314771-88-5
Orukọ Kemikali | (S)-N- (3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy) quinazolin-4-Amine |
Awọn itumọ ọrọ sisọ | N- (3-Chloro-4-Fluorophenyl) -6-Nitro-7-[(3S) -oxolan-3-yl] oxyquinazolin-4-Amine;7-((S) -Tetrahydrofuran-3-yloxy) -4- (3-Chloro-4-Fluorophenyl) amino-6-Nitroquinazoline;Afatinib Aimọ |
Nọmba CAS | 314771-88-5 |
NỌMBA CAT | RF-PI2027 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C18H14ClFN4O4 |
Òṣuwọn Molikula | 404.78 |
iwuwo | 1.534 ± 0.060 g / cm3 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Yellow to Light Yellow Powder |
Mimọ / Analysis Ọna | > 99.0% (HPLC) |
Pipadanu lori Gbigbe | <0.50% |
Olukuluku Aimọ | <0.50% |
Lapapọ Awọn Aimọ | <1.00% |
Awọn irin Heavy | ≤20ppm |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji ti Afatinib Dimaleate (CAS: 850140-73-7) |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
(S) -N- (3-Chloro-4-Fluorophenyl) -6-Nitro-7- ((Tetrahydrofuran-3-yl) oxy) quinazolin-4-Amine (CAS: 314771-88-5) ni a lo ninu igbaradi Afatinib Dimaleate (CAS: 850140-73-7).Afatinib jẹ oogun akàn ti o ni imotuntun ti ibi-afẹde, iran tuntun ti oogun ibi-afẹde ẹnu, oogun akọkọ egboogi-akàn ni agbaye ti o sopọ mọ idile ErbB, ti o munadoko diẹ sii ati ibi-afẹde Dina ifihan agbara ti o nfa idagba ti awọn sẹẹli alakan. , idinku tabi idaduro itankale awọn sẹẹli alakan.Afatinib jẹ ti kilasi awọn oogun ti a mọ si awọn inhibitors tyrosine kinase.O ṣiṣẹ nipa didi iṣẹ ti awọn ọlọjẹ meji ti o ni ibatan pẹkipẹki, olugba idagba idagbasoke ti epidermal (EGFR) ati olugba idagba idagba eniyan 2 (HER2).Ti a lo fun itọju laini akọkọ ti awọn alaisan ti o ni akàn ẹdọfóró ti kii-kekere sẹẹli.Afatinib jẹ oogun akàn ti o ni imotuntun ti ibi-afẹde, iran tuntun ti oogun ibi-afẹde ẹnu, oogun akọkọ egboogi-akàn ni agbaye ti o sopọ mọ idile ErbB, ti o munadoko diẹ sii ati ibi-afẹde Dina ifihan agbara ti o nfa idagba ti awọn sẹẹli alakan. , idinku tabi idaduro itankale awọn sẹẹli alakan.