Anastrozole CAS 120511-73-1 API Factory Didara Giga Aworan Ifihan

Anastrozole CAS 120511-73-1 API Factory High Quality

Apejuwe kukuru:

Orukọ: Anastrozole

CAS: 120511-73-1

Irisi: Funfun si Paa-White Crystalline Powder

Ayẹwo: 98.0% ~ 102.0%

AnastrozoleItoju fun Breast Cancer

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Apejuwe:

Ipese Olupese pẹlu Iwa-mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Anastrozole
CAS: 120511-73-1

Kemikali Properties:

Oruko	Anastrozole
Awọn itumọ ọrọ sisọ	Arimidex;α, α, α', α'-Tetramethyl-5- (1H-1,2,4-triazol-1-ylmethyl) -1,3-benzenediacetonitrile
Nọmba CAS	120511-73-1
NỌMBA CAT	RF-API74
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular	C17H19N5
Òṣuwọn Molikula	293.37
Solubility	Soluble ni DMSO ati Ethanol
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun lati Pa-White Crystalline Powder
Idanimọ A	IR/MS Ni ibamu pẹlu boṣewa itọkasi
Idanimọ B	HPLC ati apẹrẹ ti o ga julọ: Ni ibamu si itọkasi
Ojuami Iyo	81.0 ~ 84.0 ℃
Akoonu Omi (nipasẹ KF)	≤0.30%
Aloku lori Iginisonu	≤0.10%
Pipadanu lori Gbigbe	≤0.50%
Awọn irin Heavy	≤10ppm
Awọn nkan ti o jọmọ
Aimọ́ A	≤0.10%
Aimọ́ B	≤0.20%
Iwa aimọ C	≤0.20%
Àìmọ́ D	≤0.10%
Aimọ́ E	≤0.10%
Nikan Miiran Aimọ	≤0.10%
Lapapọ Awọn Aimọ	≤0.50%
Awọn ohun elo ti o ku
Cyclohexane	≤0.30%
Ethyl acetate	≤0.50%
Ayẹwo	98.0% ~ 102.0% (lori ipilẹ ti o gbẹ)
Igbesi aye selifu	24 osu
Igbeyewo Standard	Standard Enterprise;United States Pharmacopoeia (USP) Standard
Lilo	Itoju fun Breast Cancer

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

FAQ:

Ohun elo:

Anastrozole (CAS 120511-73-1), jẹ ti kii-sitẹriọdu, iran kẹta achiral triazole itọsẹ fun tita bi ARIMIDEX® nipasẹ AstraZeneca Pharmaceuticals LP1.O jẹ ọkan ninu awọn oludena aromatase iran-kẹta ti o jẹ idije ti o ga julọ ati ti o yan ti aromatase, nitorina ni idinamọ iyipada ti testosterone sinu estradiol ati androstenedione sinu estrone.Idinamọ ti enzymu aromatase waye ni pataki nipasẹ isọdọkan ifigagbaga ti aromatase si ẹgbẹ hemegroup ti cytochrome P450, idinku biosynthesis estrogen ni awọn sẹẹli agbeegbe ti ara ati ninu ọmu.

Anastrozole jẹ itọju ti o farada ni gbogbogbo fun alakan igbaya ipele-ibẹrẹ.Gẹgẹbi awọn inhibitors aromatase miiran, ipa buburu ti o ṣe pataki julọ jẹ ewu ti o pọ si ti awọn fifọ egungun, eyiti o jẹ ihamọ fun anastrozole si akoko itọju naa.O ti iwa ni majele ti ìwọnba nigba akawe pẹlu kimoterapi;sibẹsibẹ, o ti ṣe akiyesi pe diẹ sii awọn alaisan ti a tọju pẹlu anastrozole ti rojọ ti awọn aami aisan apapọ ju ti a ti ṣe yẹ lọ, paapaa lile oni-nọmba ti o jọra si ti arthritis rheumatoid.Diẹ ninu awọn idanwo ile-iwosan ti anastrozole fun awọn obinrin postmenopausal ti o ni ọgbẹ igbaya ni Yuroopu ati awọn ipinlẹ Amẹrika royin awọn rudurudu ti iṣan bi awọn iṣẹlẹ buburu.Anastrozole (Arimidex®) jẹ inhibitor aromatase ti a fọwọsi ni EU, AMẸRIKA ati ni awọn orilẹ-ede miiran ni agbaye fun lilo bi itọju adjuvant ni awọn obinrin postmenopausal ti o ni ibẹrẹ-ipele, akàn igbaya receptor-positive hormone.O tun fọwọsi ni EU ati awọn orilẹ-ede miiran ni agbaye fun itọju ajẹmọra ti o tẹsiwaju ninu awọn obinrin ti o ti ni ọdun 2-3 tẹlẹ ti itọju tamoxifen adjuvant fun akàn igbaya.