Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant
Olupese Ipese Argatroban Awọn agbedemeji ibatan:
Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Argatroban Anhydrous CAS 74863-84-6
Orukọ Kemikali | Argatroban |
Awọn itumọ ọrọ sisọ | Argatroban Anhydrous |
Nọmba CAS | 74863-84-6 |
NỌMBA CAT | RF-API67 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram |
Fọọmu Molecular | C23H36N6O5S |
Òṣuwọn Molikula | 508.63 |
Ojuami Iyo | 188.0 ~ 189.0 ℃ |
Ojuami farabale | 801.3ºC ni 760 mmHg |
iwuwo | 1,47 g / cm3 |
Sowo Ipò | Sowo Labẹ Ibaramu otutu |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun lati Pa-White Crystalline Powder |
HPLC idanimọ | Akoko idaduro ti tente oke opo ti a gba lati ojutu Idanwo ni ibamu pẹlu eyiti o gba lati ojutu Standard, bi idanwo ni Assay |
Idanimọ IR | Ni ibamu si IR Spectrum ti AG RS |
Idanimọ UV | Ni aaye 259nm ati 332nm aaye igbi yẹ ki o ni gbigba ti o pọju |
Omi | 2.5-4.5% |
Solusan Awọ & wípé | Solusan yẹ ki o jẹ Clear Colorles |
Ṣe ibatan Awọn nkan | |
Aimọ A + Aimọ H | ≤0.10% |
Aimọ́ B | ≤0.10% |
Aimọ C + Aimọ E | ≤0.10% |
Àìmọ́ D | ≤0.10% |
Aimọ́ I | ≤0.10% |
Bach ti aimọ ti ko ni pato | ≤0.10% |
Lapapọ Awọn Aimọ | ≤0.30% |
Awọn ohun elo ti o ku | |
kẹmika kẹmika | ≤3000ppm |
Ethanol | ≤5000ppm |
Dichloromethane | ≤600ppm |
Ethyl acetate | ≤5000ppm |
Enantiomer (HPLC) | ≤0.10% |
Ipin Isomer (HPLC) | 30.0% -40.0% |
Kloride | ≤0.01% |
Aloku lori Iginisonu | ≤0.10% |
Awọn irin Heavy | ≤10ppm |
Awọn endotoxins kokoro arun | <5EU/mg |
Makirobia Ifilelẹ | TAMC ≤1000 cfu/g |
Ayẹwo | 98.0% -102.0% (lori ipilẹ anhydrous) |
Igbeyewo Standard | Standard Enterprise |
Lilo | API, Sintetiki Antithrombotic Aṣoju Anticoagulant |
Package: Igo, apo apamọwọ Aluminiomu, Ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti Argatroban (CAS: 74863-84-6) pẹlu didara giga, API.
Argatroban (CAS: 74863-84-6) jẹ aṣoju antithrombotic sintetiki tuntun ti o wulo ni itọju anticoagulation wọn ọpọlọ ischemic ati itankale coagulation inu iṣan.O jẹ anticoagulant ti o jẹ oludena thrombin taara moleku kekere.Ni ọdun 2000, argatroban ni iwe-aṣẹ nipasẹ Awọn ipinfunni Ounje ati Oògùn (FDA) fun prophylaxis tabi itọju thrombosis ni awọn alaisan ti o ni thrombocytopenia ti o fa heparin (HIT).Ni ọdun 2002, o fọwọsi fun lilo lakoko awọn ilowosi iṣọn-alọ ọkan ni awọn alaisan ti o ni HIT tabi ti o wa ninu eewu fun idagbasoke rẹ.Ni 2012, o ti fọwọsi nipasẹ MHRA ni UK fun anticoagulation ni awọn alaisan ti o ni heparin-induced thrombocytopenia Iru II (HIT) ti o nilo itọju ailera antithrombotic parenteral.