Aripiprazole Intermediate CAS 129722-34-5 Mimọ>98.0% (HPLC)
Olupese Ipese Intermediates ti Aripiprazole Pẹlu Giga Mimo
Aripiprazole API CAS 129722-12-9
1- (2,3-Dichlorophenyl) piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7- (4-Bromobutoxy) -3,4-Dihydro-2 (1H) - Quinolinone CAS 129722-34-5
| Orukọ Kemikali | 7- (4-Bromobutoxy) -3,4-Dihydro-2 (1H) -Quinolinone |
| Awọn itumọ ọrọ sisọ | 7- (4-Bromobutoxy) -3,4-Dihydroquinolin-2 (1H) -ọkan;7- (4-Bromobutoxy) -1,2,3,4-Tetrahydro-2-Oxoquinoline;3,4-Dihydro-7- (4-Bromobutoxy) -2 (1H) -Quinolinone;Aripiprazole aimọ 3 |
| Nọmba CAS | 129722-34-5 |
| NỌMBA CAT | RF-PI2269 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Ilana molikula | C13H16BrNO2 |
| Òṣuwọn Molikula | 298.18 |
| iwuwo | 1,383 g / cm3 |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun tabi Bia Yellow Crystal Powder |
| Mimọ / Analysis Ọna | > 98.0% (HPLC) |
| Ojuami Iyo | 110.0 ~ 114.0 ℃ |
| Pipadanu lori Gbigbe | <1.00% |
| Aloku lori Iginisonu | <0.50% |
| Awọn irin Heavy (gẹgẹbi Pb) | ≤20ppm |
| Proton NMR julọ.Oniranran | Ni ibamu si Eto |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Agbedemeji ti Aripiprazole (CAS: 129722-12-9) |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
7- (4-Bromobutoxy) -3,4-Dihydro-2 (1H) -Quinolinone (CAS: 129722-34-5) jẹ agbedemeji ni iṣelọpọ ti Aripiprazole (CAS: 129722-12-9).Ọja ibajẹ ni awọn tabulẹti Aripiprazole.Aripiprazole (Abilify).Hunting, longactingaripiprazole (itọsẹ arylpiperazine quinolinone), han lati jẹ agonist apa kan ti awọn olugba D2 (ie, ṣe itọsi awọn olugba D2 kan lakoko ti o dina awọn miiran da lori awọn ipo wọn ni ọpọlọ ati ifọkansi ti oogun).Bioavailability ti Aripiprazole wa ni ayika 87%, pẹlu ifọkansi pilasima ti o ga julọ ti waye ni awọn wakati 3 si 5 lẹhin iwọn lilo.O ti wa ni metabolized nipasẹ gbigbẹ, oxidative hydroxylation, ati N-dealkylation, ti o tobi julo nipasẹ awọn CYPs ẹdọ 3A4 ati 2D6.Fun itọju schizophrenia ati awọn rudurudu psychotic ti o ni ibatan.antagonist olugba D2 dopamine ti o yan pẹlu iṣẹ agonist autoreceptor dopamine.Antipsychotic.
