Atazanavir CAS 198904-31-3 Mimọ ≥99.0% API Factory Anti-HIV HIV-1 Inhibitor Protease
Ipese pẹlu Iwa mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Atazanavir
CAS: 198904-31-3
HIV-1 Protease Inhibitor
API Didara Giga, Iṣelọpọ Iṣowo
Orukọ Kemikali | Atazanavir |
Awọn itumọ ọrọ sisọ | BMS-232632 |
Nọmba CAS | 198904-31-3 |
NỌMBA CAT | RF-API70 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram |
Fọọmu Molecular | C38H52N6O7 |
Òṣuwọn Molikula | 704.86 |
Ojuami Iyo | 207.0 ~ 209.0 ℃ |
Solubility | Soluble ni DMSO;Ailopin ninu Omi |
Ibi ipamọ igba pipẹ | Tọju Igba pipẹ ni -20 ℃ |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun Powder |
Fọọmu | Ipilẹ ọfẹ |
Pipadanu lori Gbigbe | ≤0.50% |
Aloku lori Iginisonu | ≤0.20% |
Awọn irin Heavy | ≤20ppm |
Aimọ́ A | ≤0.10% |
Aimọ́ B | ≤0.10% |
Aimọ Kanṣoṣo | ≤0.20% |
Lapapọ Awọn Aimọ | ≤1.0% |
Mimọ / Analysis Ọna | ≥99.0% (HPLC) |
pH | 5.0 ~ 8.0 |
Igbeyewo Standard | Standard Enterprise |
Lilo | HIV-1 Protease inhibitor Anti-HIV |
Package: Igo, apo apamọwọ Aluminiomu, Ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
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Atazanavir (CAS 198904-31-3) jẹ antiretroviral, aramada ati oogun azapeptide ti o lagbara ti kilasi inhibitor protease (PI).O ti ta labẹ orukọ iṣowo Reyataz.Gẹgẹbi awọn antiretrovirals miiran, a lo lati ṣe itọju ikolu ti ọlọjẹ ajẹsara ajẹsara eniyan iru 1 (HIV-1) enzymu protease pẹlu idinamọ igbagbogbo Ki ti 66 nmol/L ati pe o tun ṣe idiwọ atunda gbogun ti HIV-1 pẹlu 50% ifọkansi ti o munadoko EC50 lati ọdọ. 2.6 si 5.3 nmol/L.Atazanavir sopọ mọ HIV-1 protease idilọwọ awọn cleavage ti gag ati gag-pol polyproteins, eyi ti àbábọrẹ ni dida awọn virions immature ni HIV-1-ikolu awọn sẹẹli.Atazanavir ni eto kemikali alamimọ C-2 ti o yatọ ati agbara gbogbogbo antiretroviral ni ọpọlọpọ awọn igara HIV ni akawe si awọn inhibitors protease miiran, pẹlu Indinavir, Nelfinavir, Ritonavir, Saquinavir ati Amprenavir.Atazanavir ṣe iyatọ si awọn PI miiran ni pe o le fun ni ni ẹẹkan-ojoojumọ ati pe o ni awọn ipa ti o kere si lori profaili ọra alaisan.Gẹgẹbi awọn inhibitors protease miiran, a lo nikan ni apapo pẹlu awọn oogun HIV miiran.Atazanavir jẹ aramada azapeptide HIV protease inhibitor.Antiviral.O ti wa ni mu nipa ẹnu lẹẹkan ọjọ kan.
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