Atazanavir Sulfate CAS 229975-97-7 Mimọ ≥99.0% API Factory Anti-HIV HIV-1 Inhibitor Protease

Apejuwe kukuru:

Orukọ Kemikali: Atazanavir Sulfate

CAS: 229975-97-7

Irisi: Funfun tabi Paa-White Powder

Mimọ: ≥99.0%

HIV-1 Protease Inhibitor

API Didara Giga, Iṣelọpọ Iṣowo

Inquiry: alvin@ruifuchem.com


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ọja Tags

Apejuwe:

Ipese pẹlu Iwa mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Atazanavir Sulfate
CAS: 229975-97-7
HIV-1 Protease Inhibitor
API Didara Giga, Iṣelọpọ Iṣowo

Kemikali Properties:

Orukọ Kemikali Sulfate Atazanavir
Awọn itumọ ọrọ sisọ BMS-232632 imi-ọjọ
Nọmba CAS 229975-97-7
NỌMBA CAT RF-API71
Iṣura Ipo Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular C38H52N6O7.H2SO4
Òṣuwọn Molikula 802.93
Ojuami Iyo 195.0 ~ 198.0 ℃
Solubility Insoluble in Water, Soluble in DMSO
Ibi ipamọ igba pipẹ Tọju Igba pipẹ ni -20 ℃
Brand Ruifu Kemikali

Awọn pato:

Nkan Awọn pato
Ifarahan Funfun tabi Pa-White Powder
Sulfate 12.0 ~ 12.5%
Pipadanu lori Gbigbe ≤0.50%
Aloku lori Iginisonu ≤0.10%
Awọn irin Heavy ≤20ppm
Aimọ Kanṣoṣo ≤0.30%
Lapapọ Awọn Aimọ ≤1.0%
Mimọ / Analysis Ọna ≥99.0% (HPLC)
pH 5.0 ~ 8.0
Igbeyewo Standard Standard Enterprise
Lilo HIV-1 Protease inhibitor Anti-HIV

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, Ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

1

FAQ:

Ohun elo:

Atazanavir Sulfate (BMS-232632 Sulfate) (CAS: 229975-97-7) jẹ fọọmu iyọ sulfate ti atazanavir ti o jẹ oludena protease HIV-1 ti o yan pupọ, jẹ oludena protease akọkọ ti a fọwọsi fun iṣakoso lẹẹkan lojoojumọ.Sulfate Atazanavir jẹ sobusitireti ati inhibitor ti CYP3A4, ati inhibitor ati inducer ti P-glycoprotein (P-gp).Atazanavir Sulfate tun jẹ inhibitor SARS-CoV 3CLpro pẹlu IC50 ti 3.49 μM.Atazanavir Sulfate jẹ azapeptide ati inhibitor HIV-protease ti o lo ninu itọju awọn akoran HIV ati Arun Kogboogun Eedi ni apapo pẹlu Awọn Aṣoju Anti-HIV miiran, ti ni idagbasoke ati ifilọlẹ nipasẹ Bristol-Myers Squibb (BMS), labẹ iwe-aṣẹ agbaye lati Novartis, fun itọju ti kokoro HIV.A ṣe ifilọlẹ Atazanavir ni AMẸRIKA bi Reyataz™ ni Oṣu Keje ọdun 2003. Antiviral.Atazanavir ti fihan pe o ni agbara diẹ sii ju marun ti a fọwọsi lọwọlọwọ awọn inhibitors protease HIV-1.Atazanavir yiyan ṣe idiwọ sisẹ-pato ọlọjẹ ti gbogun ti Gag ati Gag-Pol polyproteins ninu awọn sẹẹli ti o ni kokoro HIV-1 nipa didi si aaye ti nṣiṣe lọwọ ti protease HIV-1, nitorinaa idilọwọ dida awọn virions ogbo.Atazanavir ko ṣiṣẹ lodi si HIV-2.

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