Bicalutamide CAS 90357-06-5 API Factory High Didara To ti ni ilọsiwaju Prostate Cancer Afihan Aworan

Bicalutamide CAS 90357-06-5 API Factory Didara Giga Akàn Prostate Prostate

Apejuwe kukuru:

Orukọ: Bicalutamide

CAS: 90357-06-5

Irisi: Funfun si Paa-White Crystalline Powder

Ayẹwo: 98.0% ~ 102.0%

Bicalutamide ni itọju ti To ti ni ilọsiwaju Prostate Cancer

API Didara Giga, Iṣelọpọ Iṣowo

Inquiry: alvin@ruifuchem.com

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ọja Tags

Apejuwe:

Ipese Olupese pẹlu Iwa-mimọ giga ati Didara Idurosinsin
Orukọ: Bicalutamide
CAS: 90357-06-5
Bicalutamide ni itọju ti To ti ni ilọsiwaju Prostate Cancer
API Didara Giga, Iṣelọpọ Iṣowo

Kemikali Properties:

Oruko	Bicalutamide
Awọn itumọ ọrọ sisọ	N-[4-Cyano-3- (trifluoromethyl) phenyl] -3-[(4-fluorophenyl) sulfonyl] -2-hydroxy-2-methylpropionamide
Nọmba CAS	90357-06-5
NỌMBA CAT	RF-API76
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular	C18H14F4N2O4S
Òṣuwọn Molikula	430.37
Ibi ipamọ otutu	2-8℃
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun lati Pa-White Crystalline Powder
Idanimọ A	IR: Spectrum ti ayẹwo ni ibamu si ti boṣewa itọkasi
Idanimọ B	HPLC: Akoko idaduro ti oke pataki ti ojutu ayẹwo ni ibamu si ti ojutu boṣewa
Idanimọ C	Organic Fluoride Idanimọ
Solubility	Soluble Larọwọto ni Acetone ati Tetrahydrofuran, Soluble Diẹ ninu Ethyl Acetate
Ojuami Iyo	191.0 ~ 195.0 ℃
Akoonu Omi (nipasẹ KF)	≤0.20%
Akoonu fluoride	15.9% ~ 18.5%
Pipadanu lori Gbigbe	≤0.50%
Aloku lori Iginisonu	≤0.10%
Awọn irin Heavy	≤10ppm
Awọn ohun elo ti o ku
Tetrahydrofuran	≤0.072%
Toluene	≤0.089%
N-Hexane	≤0.029%
Acetone	≤0.50%
Ethyl acetate	≤0.50%
Awọn nkan ti o jọmọ
N, N'-Dimethyl Acetamide	≤0.109%
Bicalutamide Aminobenzonitrile	≤0.10%
Agbo ti o jọmọ Bicalutamide A Isomer A	≤0.10%
Agbo ti o jọmọ Bicalutamide A Isomer B	≤0.10%
Desfluoro Bicalutamide	≤0.20%
2-Fluoro Bicalutamide	≤0.20%
Deoxy Bicalutamide	≤0.20%
Bicalutamide Sulfide	≤0.10%
Eyikeyi Aisọye Aimọ	≤0.10%
Lapapọ Awọn Aimọ	≤0.50%
Patiku Iwon	90% <10um;50% <5um
Ayẹwo	98.0% ~ 102.0% (lori ipilẹ ti o gbẹ)
Awọn Idanwo Microbiological
Lapapọ le yanju Aerobic kika	≤500CFU/g
Iwukara ati Molds	≤50CFU/g
Igbesi aye selifu	24 osu
Igbeyewo Standard	Standard Enterprise;USP Standard
Lilo	API, ni itọju To ti ni ilọsiwaju Prostate Cancer

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

FAQ:

Ohun elo:

Bicalutamide (CAS: 90357-06-5) jẹ antagonist androgen ti kii ṣe sitẹriọdu, eyiti o dije fun olugba androgen pẹlu androgen, ṣe idiwọ gbigba cellular ti androgen, ati idinamọ sisopọ awọn androgens si eto-ara ti a pinnu.O sopọ pẹlu olugba androgen ti o ṣe agbekalẹ eka olugba, eyiti o wọ inu arin ati ni idapo pẹlu nucleoprotein, nitorinaa ṣe idiwọ idagbasoke sẹẹli tumo.O le jẹ bi oogun laini akọkọ fun itọju palliative ti akàn pirositeti to ti ni ilọsiwaju.Bicalutamide ti ṣe ifilọlẹ ni United Kingdom, ọja agbaye akọkọ rẹ, fun itọju akàn pirositeti to ti ni ilọsiwaju ni apapọ pẹlu afọwọṣe LHRH tabi simẹnti abẹ.Ti kii-sitẹriọdu, antiandrogen ti o yan ni agbeegbe, bicalutamide ṣe idiwọ iṣe ti dihydrotestosterone ati testosterone ni awọn aaye ibi-afẹde nipasẹ isunmọ ifigagbaga si olugba androgen cytosolic.O ti ni ifitonileti daradara pẹlu ko si pataki ti iṣan inu ọkan ati awọn ipa ẹgbẹ ti iṣelọpọ nitori anfani ti aini eyikeyi iṣẹ ṣiṣe sitẹriọdu.Awọn ipa ti bicalutamide bi monotherapy ti ṣe afihan ni ile-iwosan.Awọn oṣuwọn idahun ti o ni ileri ni a tun royin ni itọju awọ, igbaya, pancreas ati awọn aarun ẹdọfóró sẹẹli ti kii-kekere.