Bortezomib CAS 179324-69-7 Mimo ≥99.0% (HPLC) API Iwa Mimo giga
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Bortezomib CAS 179324-69-7
| Orukọ Kemikali | Bortezomib |
| Awọn itumọ ọrọ sisọ | Velcade, MG-341, PS-341 |
| Nọmba CAS | 179324-69-7 |
| NỌMBA CAT | RF-API65 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram |
| Fọọmu Molecular | C19H25BN4O4 |
| Òṣuwọn Molikula | 384.24 |
| Ojuami Iyo | 122.0 ~ 124.0 ℃ |
| iwuwo | 1.214 |
| Atọka Refractive | 1.564 |
| Solubility | Soluble ni Chloroform, DMSO, Ethanol ati Methanol |
| Iduroṣinṣin | Hygroscopic ati Ọrinrin Sensitive |
| Sowo Ipò | Sowo Labẹ Ibaramu otutu |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun tabi Pa-White Powder |
| Mimọ / Analysis Ọna | ≥99.0% (HPLC) |
| Pipadanu lori Gbigbe | ≤0.50% |
| Aloku lori Iginisonu | ≤0.20% |
| Yiyi opitika | -41,0 ° ~ -46,0 ° |
| Eru Irin | ≤20ppm |
| Akitiyan | 4.0 ~ 7.0 |
| Isomer | ≤0.50% |
| Aimọ Kanṣoṣo | ≤0.50% |
| Lapapọ Awọn Aimọ | ≤1.0% |
| Awọn ohun elo ti o ku | |
| kẹmika kẹmika | ≤0.30% |
| Dichloromethane | ≤0.05% |
| Hexane | ≤0.02% |
| Ethyl acetate | ≤0.50% |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | API |
Package: Igo, apo apamọwọ Aluminiomu, Ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti Bortezomib (CAS: 179324-69-7) pẹlu didara giga, API.
Bortezomib, ti a ta labẹ orukọ iyasọtọ Velcade laarin awọn miiran, jẹ oogun egboogi-akàn ti a lo lati ṣe itọju ọpọ myeloma ati lymphoma cell mantle.Bortezomib jẹ ifọwọsi fun lilo iṣoogun ni Amẹrika ni ọdun 2003 ati ni European Union ni ọdun 2004. O wa lori Akojọ Ajo Agbaye ti Ilera ti Awọn oogun pataki.Bortezomib ni akọkọ proteasome onidalẹkun lati wa ni a fọwọsi b awọn US FDA fun ọpọ myeloma, a ẹjẹ akàn.Oludanu ti o le yi pada ti 26S proteasome-patiku amuaradagba multiprotein ti o ni awọ agba ti a rii ni arin ati cytosol ti gbogbo awọn sẹẹli eukaryotic.Bortezomib jẹ yiyan ati logan 26S proteasome inhibitor, iyẹn jẹ itọsẹ dipeptide boronic acid.Awọn iwadii sẹẹli alakan pancreatic eniyan ṣe afihan Bortezomib lati ṣe idiwọ PKR-like endoplasmic reticulum (ER) kinase ati mu aapọn ER mu, ti o yori si apoptosis.
