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Brigatinib CAS 1197953-54-0 Mimọ> 99.0% (HPLC) Aworan Ifihan
  • Brigatinib CAS 1197953-54-0 Mimọ> 99.0% (HPLC)

Brigatinib CAS 1197953-54-0 Mimọ> 99.0% (HPLC)

Apejuwe kukuru:

Orukọ Kemikali: Brigatinib

Awọn itumọ ọrọ sisọ: AP-26113

CAS: 1197953-54-0

Mimọ:> 99.0% (HPLC)

Irisi: Funfun si Paa-White Powder

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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1197953-54-0 -Apejuwe:

Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ ti Brigatinib (AP-26113) (CAS: 1197953-54-0) pẹlu didara to gaju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra Brigatinib,Please contact: alvin@ruifuchem.com

1197953-54-0 -Kemikali Properties:

Orukọ Kemikali Brigatinib
Awọn itumọ ọrọ sisọ AP26113;AP-26113;5-Chloro-N4-[2- (Dimethylphosphinyl) phenyl] -N2-[2-Methoxy-4-[4- (4-Methyl-1-Piperazinyl) -1-Piperidinyl] phenyl] -2,4-Pyrimidinediamine
Iṣura Ipo Ni Iṣura, Iṣowo Iṣowo
Nọmba CAS 1197953-54-0
Fọọmu Molecular C29H39ClN7O2P
Òṣuwọn Molikula 584,09 g / mol
Ojuami Iyo > 203 ℃ (oṣu kejila)
iwuwo 1,31 ± 0,10 g / cm3
COA & MSDS Wa
Ipilẹṣẹ Shanghai, China
Brand Ruifu Kemikali

1197953-54-0 -Awọn pato:

Awọn nkan Awọn pato Esi
Ifarahan Funfun to Pa-White Powder Ibamu
Mimọ / Analysis Ọna > 99.0% (HPLC) 99.26%
O pọju.Aimọ Kanṣoṣo <1.00% 0.25%
Pipadanu lori Gbigbe <1.00% 0.27%
Infurarẹẹdi julọ.Oniranran Ni ibamu pẹlu Eto Ibamu
1H NMR julọ.Oniranran Ni ibamu pẹlu Eto Ibamu
Ipari Ọja naa ti ni idanwo ati ni ibamu pẹlu awọn pato ti a fun

Package/Ipamọ/Gbigbe:

Apo:Igo Fluorinated, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati fipamọ sinu itura, gbigbẹ ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.

Awọn anfani:

Agbara to to: Awọn ohun elo to ati awọn onimọ-ẹrọ

Iṣẹ Ọjọgbọn: Iṣẹ rira iduro kan

OEM Package: Aṣa package ati aami wa

Ifijiṣẹ Yara: Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta

Ipese Idurosinsin: Ṣetọju ọja iṣura ti o tọ

Atilẹyin imọ-ẹrọ: Ojutu imọ-ẹrọ wa

Iṣẹ Iṣọkan Aṣa: Larin lati giramu si kilos

Didara to gaju: Ṣeto eto idaniloju didara pipe

FAQ:

Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.

Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.

Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.

DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl

Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.

Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.

MOQ?Ko si MOQ.Ibere ​​kekere jẹ itẹwọgba.

Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.

Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.

Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.

Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.

Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.

1197953-54-0 - Apejuwe Gbogbogbo:

Brigatinib (AP-26113) (CAS: 1197953-54-0) jẹ iwadii kekere-molecule ifọkansi itọju ailera akàn ti o dagbasoke nipasẹ ARIAD Pharmaceuticals, Inc. anaplastic lymphoma kinase (ALK).Brigatinib jẹ agonist yiyan lodi si awọn iyatọ ti EGFR ni ilodi si awọn fọọmu mutant egan.Oogun naa tun ṣe afihan yiyan si jiini idapọ ALK-EML4, eyiti o jẹ abala ipilẹ ti iyipada ti parenchyma ẹdọfóró ti o ni ifaragba.Brigatinib ni a fun ni aṣẹ fun awọn alaisan ti o ni awọn jiini aiṣedeede kan pato ati nigbati akàn ẹdọfóró ti kii-kekere kekere (NSCLC) ko ṣe idahun si iṣakoso pẹlu awọn oogun miiran.Brigatinib jẹ ipin bi oludena kinase, eyiti ilana iṣe rẹ jẹ didi iṣe ti awọn ọlọjẹ ajeji ti o mu isodipupo awọn sẹẹli alakan pọ si.

1197953-54-0 - Awọn itọkasi:

Brigatinib (CAS: 1197953-54-0) ni a fun ni aṣẹ fun awọn alaisan ti o ni awọn fọọmu kan pato ti NSCLC ti o ti tan kaakiri awọn apakan ti ara ni awọn eniyan ti o ti ni itọju iṣaaju pẹlu awọn oogun akàn miiran bii Crizotinib, ati pe ipo wọn ti buru si. tabi wọn ṣe afihan awọn ami ilọsiwaju ti o kere julọ.O wa labẹ iwadii nipataki fun ipa itọju rẹ lori akàn ẹdọfóró sẹẹli ti kii-kekere (NSCLC) nibiti ALK ti mu ṣiṣẹ ati awọn iyipada EGFP nigbagbogbo waye.

1197953-54-0 - Ohun elo:

Brigatinib (AP-26113) (CAS: 1197953-54-0) jẹ oludena iran-iran tuntun ti tyrosine kinase, ti o nfihan ipa pataki ni ALK + metastatic NSCLC.Ni Oṣu Kẹjọ Ọjọ 30, Ọdun 2016, United States FDA funni ni bugtinib gẹgẹbi itọju ailera aṣeyọri ati oogun toje fun ALK + NSCLC ni awọn alaisan ti o ti ni idagbasoke tabi ko le farada Crizotinib, itọju ALK + NSCLC akọkọ-iran.Fi ni pataki si atunyẹwo ohun elo kikojọ ati gba data ohun elo laaye lati fi silẹ lori ipilẹ yiyi.FDA fọwọsi Bugtinib ni Oṣu Kẹrin Ọjọ 28, Ọdun 2017, labẹ orukọ iṣowo Alunbrigtm.

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