Brimonidine Tartrate CAS 70359-46-5 Assay 99.0% ~ 101.0%
Shanghai Ruifu Kemikali Co., Ltd jẹ olupese ti Brimonidine Tartrate (CAS: 70359-46-5) pẹlu didara to gaju.agonist olugba olugba α2-adrenergic ti o yan, oogun ti a lo lati ṣe itọju glaucoma igun-ìmọ tabi haipatensonu oju.Kemikali Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, iṣẹ ti o dara julọ, kekere ati awọn iwọn olopobobo ti o wa.Ra Brimonidine Tartrate,Please contact: alvin@ruifuchem.com
Orukọ Kemikali | Brimonidine Tartrate |
Awọn itumọ ọrọ sisọ | Brimonidine L-Tartrate;UK 14304 Tartrate;AGN190342 Tartrate;5-Bromo-N- (4,5-Dihydro-1H-Imidazol-2-yl) quinoxalin-6-Amine Tartrate;5-Bromo-N- (4,5-Dihydro-1H-Imidazol-2-yl) -6-Quinoxalinamine Tartrate;5-Bromo-N- (4,5-Dihydro-1H-Imidazol-2-yl) quinoxalin-6-Amine (2R,3R) -2,3-Dihydroxysuccinate |
Iṣura Ipo | Ni Iṣura, Iṣowo Iṣowo |
Nọmba CAS | 70359-46-5 |
Fọọmu Molecular | C11H10BrN5·C4H6O6 |
Òṣuwọn Molikula | 442,23 g / mol |
Ojuami Iyo | 207.0 ~ 208.0 ℃ (oṣu kejila) |
Ni imọlara | Afẹfẹ Sensitive, Ooru kókó |
COA & MSDS | Wa |
Ipilẹṣẹ | Shanghai, China |
Igbesi aye selifu | Awọn oṣu 24 ti o ba fipamọ daradara |
Ẹka | API (Ohun elo elegbogi ti nṣiṣẹ lọwọ) |
Brand | Ruifu Kemikali |
Awọn nkan | Awọn pato | Esi |
Ifarahan | Funfun tabi die-die Yellowish tabi Die-die Brownish lulú | Ni ibamu |
Idanimọ A | Specific Optical Yiyi | Ni ibamu |
Idanimọ B | Spectrophotometry gbigba infurarẹẹdi | Ni ibamu |
Solubility | Tiotuka ninu omi, ni iṣe ti ko ṣee ṣe ninu ethanol anhydrous ati ninu toluene | Ni ibamu |
Specific Optical Yiyi | +9.0° ~ +10.5° | +9,6° |
Pipadanu lori Gbigbe | ≤0.50% | 0.20% |
Sulfated Ash | ≤0.20% | 0.07% |
Awọn irin Heavy | ≤20ppm | <20ppm |
Awọn nkan ti o jọmọ | ||
Pato Egbin | ||
N-(imidazolidin2ylidene) quinoxalin-6-amine | ≤0.10% | Ni ibamu |
5-bromoqulinoxalin-6-amin | ≤0.10% | Ni ibamu |
Quinoxalin-6-amin | ≤0.10% | Ni ibamu |
1- (5-bromoquinoxalin-6-yl) thiourea | ≤0.10% | Ni ibamu |
2- (5-bromoquinoxalin-6-yl) guanidine | ≤0.10% | Ni ibamu |
5-bromo-N-(1H-imidazol-2-yl)Quinoxalin-6-amine | ≤0.10% | Ni ibamu |
1- (2-aminoethyl) -3- (5-bromoquinoxalin-6-yl) urea | ≤0.10% | Ni ibamu |
Àìsọ pàtó | ≤0.10% | Ni ibamu |
Lapapọ | ≤0.20% | 0.12% |
Ayẹwo | 99.0% ~ 101.0%(lori Gbẹgbẹ) | 99.8% |
Ipari | Ọja yii nipasẹ awọn ibamu ayewo pẹlu Standard BP2015 |
Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki apo eiyan naa ni wiwọ ni pipade ati tọju ni itura, gbẹ (2 ~ 8℃) ati ile-itaja ti o ni afẹfẹ daradara kuro ninu awọn nkan ti ko ni ibamu.Yago fun ifihan si orun taara, ọrinrin ati ooru ti o pọju.
Gbigbe:Firanṣẹ si agbaye nipasẹ afẹfẹ, nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
Awọn Gbólóhùn Ewu H301: Majele ti o ba gbemi.
Awọn Gbólóhùn Iṣọra
P501: Sọ awọn akoonu / eiyan silẹ si ile-iṣẹ idalẹnu ti a fọwọsi.
P270: Maṣe jẹ, mu tabi mu siga nigba lilo ọja yii.
P264: Wẹ awọ ara daradara lẹhin mimu.
P301 + P310 + P330: TI O BA mì: Lẹsẹkẹsẹ pe ile-iṣẹ POISON/dokita.Fi omi ṣan ẹnu.
P405: Itaja pa soke.
Awọn ofin ti o jọmọ:
Alaye irinna:
UN Nọmba (DOT-AIR) UN2811
Kilasi (DOT-AIR) 6.1
Iṣakojọpọ Group (TCI-A) III
HS Nọmba 2933.29.9000
Brimonidine Tartrate (CAS: 70359-46-5) jẹ olutọpa α2-receptor ti o yan pupọ, ti o ni idagbasoke nipasẹ Allergan Ile-iṣẹ AMẸRIKA, eyiti o jẹ oogun oju.O le dinku titẹ intraocular (IOP).Brimonidine Tartrate ophthalmic ojutu saling ni ọja jẹ fọọmu Brimonidine Tartrate, eyiti o jẹ oogun idinku IOP ti o dara fun glaucoma-igun-igun onibaje ati itọju haipatensonu ocular ti awọn alaisan, ṣugbọn fun awọn ipele IOP laser argon.Ojutu ophthalmic Brimonidine Tartrate ni ẹrọ iṣe meji ti iṣe nipa idinku iṣelọpọ arin takiti olomi ati jijẹ ipele pigmenti ti awọn idi itọju ti iṣan scleral olomi.Lẹhin sisọ sinu oju, ipa naa yarayara, ati pe o le de ibi giga nigba lilo to 2h, ati pe akoko to munadoko le ṣetọju 12h.Ẹjẹ le ṣe awari awọn ipa ti oogun nikan.Ọja yii ni iṣelọpọ akọkọ-kọja ninu ẹdọ, ati awọn metabolites ti a yọ jade ninu ito nipasẹ awọn kidinrin.Gbigba eto ati pinpin ko kan, ati pe awọn agbalagba ko nilo atunṣe iwọn lilo.Ojutu ophthalmic Brimonidine Tartrate ni akawe pẹlu awọn oludena α-blockers miiran, ọra-tiotuka jẹ kekere, lakoko ti ko rọrun lati kọja nipasẹ idena ọpọlọ-ẹjẹ ati pe ko ṣe agbejade sedation, hypotension ati awọn aati ikolu aarin ti clonidine miiran ti o jọra.Brimonidine Tartrate Ophthalmic Solusan jẹ yiyan pupọ fun awọn olugba α2-adrenergic, ati ipin α2/α1 ti isunmọ olugba jẹ diẹ sii ju awọn akoko 1000 lọ.Ipa ti awọn olugba alpha 2 le ja si isalẹ titẹ intraocular.Ati ipa ti awọn olugba alpha 1 le ja si isunmọ ti iṣan, ifasilẹ ipenpeju tabi idinku ati dilation ti ọmọ ile-iwe.Lilo igba pipẹ ti ọja yii kii yoo fa aibalẹ iyara.Ni afikun, ni akawe pẹlu β-blockers, Brimonidine Tartrate oju silẹ fun awọn ipa inu ọkan ati ẹjẹ kekere, ko ni ipa lori iṣẹ ẹdọfóró, nitorinaa o dara fun awọn alaisan alaabo β-blockers.Pẹlupẹlu, nigba lilo β-blocker nikan, ko le ṣaṣeyọri awọn idi itọju, ati pe o le mu FDA pọ si ni nigbakannaa.