Candesartan CAS 139481-59-7 Mimọ> 99.0% (HPLC) Ile-iṣẹ

Apejuwe kukuru:

Orukọ Kemikali: Candesartan

CAS: 139481-59-7

Mimọ:> 99.0% (HPLC)

Irisi: Funfun Powder

A yan Angiotensin II Olugba antagonist

Didara to gaju, iṣelọpọ Iṣowo

E-Mail: alvin@ruifuchem.com


Alaye ọja

Jẹmọ Products

ọja Tags

Apejuwe:

Kemikali Properties:

Orukọ Kemikali Candesartan
Awọn itumọ ọrọ sisọ CV-11974;2-Ethoxy-1-[[2'- (1H-tetrazol-5-yl) [1,1'-biphenyl] -4-yl]methyl] -1H-Benzimidazole-7-Carboxylic Acid;3-[[2'- (1H-Tetrazol-5-yl) biphenyl-4-yl]methyl] -2-ethoxy-3H-Benzimidazole-4-Carboxylic Acid;Candesartan M1;Candesartan Cilexetil EP Impurity G
Nọmba CAS 139481-59-7
NỌMBA CAT RF-PI1889
Iṣura Ipo Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Ilana molikula C24H20N6O3
Òṣuwọn Molikula 440.45
Brand Ruifu Kemikali

Awọn pato:

Nkan Awọn pato
Ifarahan Funfun Powder
Idanimọ-HPLC Akoko Idaduro Iru si Standard
Idanimọ-IR Iru si Standard
Mimọ / Analysis Ọna > 99.0% (HPLC)
Ojuami Iyo 183.0 ~ 185.0 ℃
Pipadanu lori Gbigbe <0.50%
Ọrinrin (KF) <0.50%
Aloku lori Iginisonu <0.50%
Awọn irin Heavy <20ppm
Olukuluku Aimọ <1.00% (HPLC)
Lapapọ Awọn Aimọ <1.00% (HPLC)
Atọka Refractive n20 / D 1.745 ~ 1.747
Igbeyewo Standard Standard Enterprise
Lilo API;Fun itọju Haipatensonu

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

Awọn anfani:

1

FAQ:

Ohun elo:

Candesartan (CAS: 139481-59-7) jẹ angiotensin II antagonist olugba pẹlu IC50 ti 0.26 nM.Ifojusi: Angiotensin II Olugba candesartan jẹ itọkasi fun itọju haipatensonu.Candesartan Cilexetil ni a fọwọsi ni akọkọ ni GB ni Oṣu Kẹrin Ọjọ 29, Ọdun 1997, lẹhinna fọwọsi nipasẹ Ile-iṣẹ Ounje ati Oògùn AMẸRIKA (FDA) ni Oṣu Karun ọjọ 4, ọdun 1998, ati fọwọsi nipasẹ Awọn elegbogi ati Ile-iṣẹ Awọn Ẹrọ Iṣoogun ti Japan (PMDA) ni Oṣu Kẹta Ọjọ 12, Ọdun 1999. O jẹ idagbasoke nipasẹ AstraZeneca, lẹhinna ṣe tita bi Atacand nipasẹ AstraZeneca ni GB ati AMẸRIKA, ati tita bi Blopress nipasẹ Takeda ni JP.Candesartan Cilexetil jẹ blocker olugba angiotensin II (ARB), o ṣe idiwọ vasoconstrictor ati awọn ipa ikọkọ aldosterone ti angiotensin II nipa yiyan dina asopọ ti angiotensin II si olugba AT1 ni ọpọlọpọ awọn ara, gẹgẹ bi isan dan ti iṣan ati ẹṣẹ adrenal.Atacand jẹ itọkasi fun itọju ti haipatensonu ninu awọn agbalagba ati awọn ọmọde 1 si <17 ọdun ti ọjọ ori, ikuna ọkan (NYHA kilasi II-IV) ati pe a lo lati dinku iku ẹjẹ ọkan ati ile iwosan ikuna ọkan.

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