Candesartan Cilexetil CAS 145040-37-5 Mimo>99.0% (HPLC) API Aworan Iṣafihan Factory

Candesartan Cilexetil CAS 145040-37-5 Mimo>99.0% (HPLC) API Factory

Apejuwe kukuru:

Orukọ Kemikali: Candesartan Cilexetil

CAS: 145040-37-5

Mimọ:> 99.0% (HPLC)

Irisi: Funfun si Paa-White Crystalline Powder

A yan Angiotensin II Olugba antagonist

API Didara Giga, Iṣelọpọ Iṣowo

E-Mail: alvin@ruifuchem.com

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ọja Tags

Apejuwe:

Ipese Kemikali Ruifu Candesartan Cilexetil Intermediate Pẹlu Iwa-mimọ giga
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Intermediate Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Intermediate CAS 139481-44-0
Triyl Candesartan Cilexetil CAS 170791-09-0

Kemikali Properties:

Orukọ Kemikali	Candesartan Cilexetil
Awọn itumọ ọrọ sisọ	TCV-116;1-((((Cyclohexyloxy) carbonyl) oxy) ethyl 1- ((2'- (1H-tetrazol-5-yl)-[1,1'-biphenyl] -4-yl)methyl) -2-ethoxy-1H -benzo [d] imidazole-7-Carboxylate
Nọmba CAS	145040-37-5
NỌMBA CAT	RF-PI1891
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Fọọmu Molecular	C33H34N6O6
Òṣuwọn Molikula	610.66
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun lati Pa-White Crystalline Powder
HPLC idanimọ	Akoko idaduro ti tente oke pataki ninu chromatogram ti ayẹwo ni ibamu si eyi ti o wa ninu chromatogram ti o gba pẹlu boṣewa
Idanimọ IR	Iwoye gbigba infurarẹẹdi IR jẹ aami kanna si ti boṣewa itọkasi Candesartan Cilexetil
Wipe ati Awọ Solusan	Solusan ni chloroform ni 5% jẹ kedere ati laisi awọ
Mimọ / Analysis Ọna	> 99.0% (HPLC)
Ojuami Iyo	155.0 ~ 160.0 ℃
Pipadanu lori Gbigbe	<0.30%
Aloku lori Iginisonu	<0.10%
Awọn irin Heavy	<10ppm
Arsenic (Bi)	<1ppm
Pipin Iwon patiku	90% <30 μm
Organic impurities	nipasẹ HPLC
Ethyl Candesartan	<0.15%
Desetyl Candesartan	<0.15%
N2-Ethyl Candesartan Cilexei	<0.15%
Eyikeyi Aimọ Aimọ	<0.15%
Lapapọ Awọn Aimọ	<0.60%
Ayẹwo nipasẹ Potentiometry	99.0 ~ 101.0% ti C33H34N6O6, ṣe iṣiro lori nkan anhydrous
Organic Iyipada Aimọ
Metano	<0.30%
Ethanol	<0.50%
Diethyl Eteri	<0.50%
Aceton	<0.50%
Dichloromethan	<0.06%
Dimethylformamide	<0.088%
Ibamu Alailowaya
Lapapọ Aerobic makirobia kika	<1000cfu/g
Molds & Iwukara	<100cfu/g
E.Coli	Ti ko si
Salmonella	Ti ko si
Igbeyewo Standard	Standard Enterprise
Lilo	API;Aṣoju Antihypertensive

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

Awọn anfani:

FAQ:

Ohun elo:

Candesartan Cilexetil (TCV-116) (CAS: 145040-37-5) jẹ antagonist olugba angiotensin II pẹlu IC50 ti 0.26 nM, ti a lo ninu itọju haipatensonu.Candesartan jẹ blocker angiotensin-receptor (ARB) ti o le ṣee lo nikan tabi pẹlu awọn aṣoju miiran lati ṣe itọju haipatensonu.O ti nṣakoso ni ẹnu bi prodrug, candesartan cilexetil, eyiti o yipada ni iyara si metabolite ti nṣiṣe lọwọ, candesartan, lakoko gbigba ninu ikun ikun.Candesartan dinku titẹ ẹjẹ nipasẹ atako si eto renin-angiotensin-aldosterone (RAAS);o ti njijadu pẹlu angiotensin II fun abuda si iru-1 angiotensin II olugba (AT1) subtype ati idilọwọ titẹ ẹjẹ ti npọ si awọn ipa ti angiotensin II.Ko dabi angiotensin-converting enzyme (ACE) inhibitors, ARBs ko ni ipa buburu ti Ikọaláìdúró gbigbẹ.Candesartan le ṣee lo lati ṣe itọju haipatensonu, haipatensonu systolic ti o ya sọtọ, hypertrophy ventricular osi ati nephropathy dayabetik.O tun le ṣee lo bi aṣoju yiyan fun itọju ikuna ọkan, ailagbara systolic, infarction myocardial ati arun iṣọn-alọ ọkan.